Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

M Hrubša, T Siatka, I Nejmanová, M Vopršalová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B1, B2, B3, and B5.
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …

Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers

CA Abbas, AA Sibirny - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
SUMMARY Riboflavin [7, 8-dimethyl-10-(1′-d-ribityl) isoalloxazine, vitamin B2] is an
obligatory component of human and animal diets, as it serves as the precursor of flavin …

Production of riboflavin and related cofactors by biotechnological processes

S Liu, W Hu, Z Wang, T Chen - Microbial cell factories, 2020 - Springer
Riboflavin (RF) and its active forms, the cofactors flavin mononucleotide (FMN) and flavin
adenine dinucleotide (FAD), have been extensively used in the food, feed and …

Riboflavin transport and metabolism in humans

M Barile, TA Giancaspero, P Leone, M Galluccio… - Journal of inherited …, 2016 - Springer
Recent studies elucidated how riboflavin transporters and FAD forming enzymes work in
humans and create a coordinated flavin network ensuring the maintenance of cellular …

Structure, function, and mechanism of proline utilization A (PutA)

LK Liu, DF Becker, JJ Tanner - Archives of biochemistry and biophysics, 2017 - Elsevier
Proline has important roles in multiple biological processes such as cellular bioenergetics,
cell growth, oxidative and osmotic stress response, protein folding and stability, and redox …

Biosynthesis of flavin cofactors in man: implications in health and disease

M Barile, T Anna Giancaspero, C Brizio… - Current …, 2013 - ingentaconnect.com
The primary role of the water-soluble vitamin B2, ie riboflavin, in cell biology is connected
with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases …

Uptake and metabolism of antibiotics roseoflavin and 8-demethyl-8-aminoriboflavin in riboflavin-auxotrophic Listeria monocytogenes

A Matern, D Pedrolli, S Großhennig… - Journal of …, 2016 - Am Soc Microbiol
The riboflavin analogs roseoflavin (RoF) and 8-demethyl-8-aminoriboflavin (AF) are
produced by the bacteria Streptomyces davawensis and Streptomyces cinnabarinus …

Direct evolution of riboflavin kinase significantly enhance flavin mononucleotide synthesis by design and optimization of flavin mononucleotide riboswitch

Y Du, X Zhang, H Zhang, R Zhu, Z Zhao, J Han… - Bioresource …, 2023 - Elsevier
Flavin mononucleotide (FMN) is the active form of riboflavin. It has a wide range of
application scenarios in the pharmaceutical and food additives. However, there are …

Development of novel experimental models to study flavoproteome alterations in human neuromuscular diseases: the effect of Rf therapy

M Tolomeo, A Nisco, P Leone, M Barile - International Journal of …, 2020 - mdpi.com
Inborn errors of Riboflavin (Rf) transport and metabolism have been recently related to
severe human neuromuscular disorders, as resulting in profound alteration of human …

Maturation of the respiratory complex II flavoprotein

P Sharma, E Maklashina, G Cecchini… - Current opinion in …, 2019 - Elsevier
Highlights•Maturation and assembly of bioenergetic complexes is critical for cellular
respiration.•Non-specific chaperones and specific assembly factors precisely coordinate the …