Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

[HTML][HTML] White adipose tissue dysfunction in obesity and aging

M Reyes-Farias, J Fos-Domenech, D Serra… - Biochemical …, 2021 - Elsevier
Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …

A single-cell atlas of human and mouse white adipose tissue

MP Emont, C Jacobs, AL Essene, D Pant, D Tenen… - Nature, 2022 - nature.com
White adipose tissue, once regarded as morphologically and functionally bland, is now
recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of …

Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans

CWY Ha, A Martin, GD Sepich-Poore, B Shi, Y Wang… - Cell, 2020 - cell.com
A mysterious feature of Crohn's disease (CD) is the extra-intestinal manifestation of"
creeping fat"(CrF), defined as expansion of mesenteric adipose tissue around the inflamed …

miRNAs as cornerstones in adipogenesis and obesity

SY Elkhawaga, A Ismail, EGE Elsakka, AS Doghish… - Life Sciences, 2023 - Elsevier
In recent decades, obesity has extensively emerged to the level of pandemics. It's
significantly associated with serious co-morbidities that could decrease life quality and even …

Adipose tissue-derived mesenchymal stem cells

BA Bunnell - Cells, 2021 - mdpi.com
The long-held belief about adipose tissue was that it was relatively inert in terms of
biological activity. It was believed that its primary role was energy storage; however, that was …

Targeting adipose tissue in the treatment of obesity-associated diabetes

CM Kusminski, PE Bickel, PE Scherer - Nature reviews Drug discovery, 2016 - nature.com
Adipose tissue regulates numerous physiological processes, and its dysfunction in obese
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …

What we talk about when we talk about fat

ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Dietary anthocyanins against obesity and inflammation

YM Lee, Y Yoon, H Yoon, HM Park, S Song, KJ Yeum - Nutrients, 2017 - mdpi.com
Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its
associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary …

Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the …

P Bourin, BA Bunnell, L Casteilla, M Dominici, AJ Katz… - Cytotherapy, 2013 - Elsevier
Background aims Adipose tissue is a rich and very convenient source of cells for
regenerative medicine therapeutic approaches. However, a characterization of the …