IL-35 regulates the function of immune cells in tumor microenvironment

K Liu, A Huang, J Nie, J Tan, S Xing, Y Qu… - Frontiers in …, 2021 - frontiersin.org
Interleukin-35 (IL-35) is a heterodimeric cytokine composed of Epstein-Barr virus-induced
gene 3 (EBI3) and IL-12p35 that has recently been shown to play diverse and important …

IL-35: New Target for Immunotherapy Targeting the Tumor Microenvironment

P Yi, W Yu, Y Xiong, Y Dong, Q Huang, Y Lin… - Molecular Cancer …, 2024 - AACR
Abstract Interleukin 35 (IL-35) is a newly discovered inhibitory cytokine of the IL12 family.
More recently, IL-35 was found to be increased in the tumor microenvironment (TME) and …

Human umbilical cord mesenchymal stem cell-derived exosomes alleviate the severity of experimental autoimmune encephalomyelitis and enhance lag-3 expression …

A Mohammadzadeh, M Lahouty, H Charkhian… - Molecular Biology …, 2024 - Springer
Background Multiple sclerosis (MS) is a complex autoimmune disease that affects the
central nervous system, causing inflammation, demyelination, and neurodegeneration …