Despite the recent advances in chemotherapeutic treatments against cancer, some types of
highly aggressive and invasive cancer develop drug resistance against conventional …

Simple Summary In this review, the history of RNA interference discovery and current
knowledge about microRNA biogenesis and post-transcriptional regulation of gene …

RNA methylation at position N6 in adenosine (m6A) and its associated methyltransferase
complex (MTC) are involved in tumorigenesis. We aimed to explore m6A biological function …

Purpose: PARP inhibitors (PARPi) are primarily effective against BRCA1/2-mutated breast
and ovarian cancers, but resistance due to reversion of mutated BRCA1/2 and other …

Esophageal squamous cell carcinoma (ESCC), the most frequent esophageal cancer (EC)
subtype, entails dismal prognosis. Hypoxia, a common feature of advanced ESCC, is …

Purpose Her-2 is an epidermal growth factor receptor expressed in some prostate cancers
(PC) associated with outgrowth of the tumor. Dysregulation of some microRNAs is involved …

Abstract Aim Long non-coding RNAs serve as key components of competing endogenous
RNA (ceRNA) networks that underlie tumorigenesis. We investigated the pathogenic roles of …

MicroRNAs (miRs) modulate the expression of target genes in the signal pathway on
transcriptome level. The present study investigated the 'epigenetic‑based miRNA (epi …

MicroRNAs (miRNAs), a class of small, non-coding RNA molecules, play an important role in
the posttranscriptional regulation of gene expression, thereby influencing important cellular …

Cadmium (Cd) is an increasingly important environmental pollutant due to its high toxicity to
fish and aquatic animals. In the present study, we cultured common carp (Cyprinus carpio L.) …