Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …

Morpholine is a versatile moiety, a privileged pharmacophore and an outstanding
heterocyclic motif with wide ranges of pharmacological activities due to different …

As of June 2020, the number of people infected with severe acute respiratory coronavirus 2
(SARS-CoV-2) continues to skyrocket, with more than 6.7 million cases worldwide. Both the …

Viral infections are among the most complex medical problems and have been a major
threat to the economy and global health. Several epidemics and pandemics have occurred …

Combination therapies have become a standard for the treatment for HIV and hepatitis C
virus (HCV) infections. They are advantageous over monotherapies due to better efficacy …

The present study aimed to assess the repurposing potential of existing antiviral drug
candidates (FDA‐approved and investigational) against SARS‐CoV‐2 target proteins that …

Viruses are the major causes of acute and chronic infectious diseases in the world.
According to the World Health Organization, there is an urgent need for better control of viral …

Viruses continue to be a major threat to human health. In the last century, pandemics
occurred and resulted in significant mortality and morbidity. Natural products have been …

Infectious diseases are one of the main global public health risks, predominantly caused by
viruses, bacteria, fungi, and parasites. The control of infections is founded on three main …

Transition state theory teaches that chemically stable mimics of enzymatic transition states
will bind tightly to their cognate enzymes. Kinetic isotope effects combined with …