Mesenchymal stem cell-derived exosomes: applications in regenerative medicine

MD Hade, CN Suire, Z Suo - Cells, 2021 - mdpi.com
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Observing Extracellular Vesicles Originating from Endothelial Cells in Vivo Demonstrates Improved Astrocyte Function Following Ischemic Stroke via Aggregation …

X Gao, H Gao, K Yue, X Cao, E Yang, Z Zhang… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) obtained from endothelial cells (ECs) have significant
therapeutic potential in the clinical management of individuals with ischemic stroke (IS) …

Alternating magnetic field-promoted nanoparticle mixing: the on-chip immunocapture of serum neuronal exosomes for Parkinson's disease diagnostics

M Sharafeldin, S Yan, C Jiang, GK Tofaris… - Analytical …, 2023 - ACS Publications
The analysis of cargo proteins in exosome subpopulations has considerable value in
diagnostics but a translatable impact has been limited by lengthy or complex exosome …

Mechanisms and biomarker potential of extracellular vesicles in stroke

N Ollen-Bittle, AD Roseborough, W Wang, JD Wu… - Biology, 2022 - mdpi.com
Simple Summary A stroke occurs when there is a lack of blood flow to the brain. Stroke
injures the brain and can have devastating outcomes depending on the size and location of …

[HTML][HTML] Exosomes derived neuronal markers: immunoaffinity isolation and characterization

G Yousif, S Qadri, A Parray, N Akhthar, A Shuaib… - Neuromolecular …, 2022 - Springer
Neuronal exosomes play a crucial role in intercellular communication in the brain and
represent a promising biomarker for neurological diseases, including stroke. However …

miR-21 in EVs from pulmonary epithelial cells promotes myofibroblast differentiation via glycolysis in arsenic-induced pulmonary fibrosis

P Wang, T Xiao, J Li, D Wang, J Sun, C Cheng… - Environmental …, 2021 - Elsevier
As an environmental toxicant, arsenic causes damage to various organs and systems of the
body and has attracted worldwide attention. It is well-known that exposure to arsenic can …

Extracellular vesicles in type 1 diabetes: A versatile tool

CN Suire, MD Hade - Bioengineering, 2022 - mdpi.com
Type 1 diabetes is a chronic autoimmune disease affecting nearly 35 million people. This
disease develops as T-cells continually attack the β-cells of the islets of Langerhans in the …

Most recent advances and applications of extracellular vesicles in tackling neurological challenges

M Kaur, S Fusco, B Van den Broek… - Medicinal Research …, 2024 - Wiley Online Library
Over the past few decades, there has been a notable increase in the global burden of
central nervous system (CNS) diseases. Despite advances in technology and therapeutic …

Multiplexing biosensor for the detection of extracellular vesicles as biomarkers of tissue damage and recovery after ischemic stroke

S Picciolini, V Mangolini, F Rodà, A Montesano… - International Journal of …, 2023 - mdpi.com
The inflammatory, reparative and regenerative mechanisms activated in ischemic stroke
patients immediately after the event cooperate in the response to injury, in the restoration of …