Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances
Widely developed for clinical screening, electrocardiogram (ECG) recordings capture the
cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first …
cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first …
[HTML][HTML] Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …
components across multiple spatial (from ion channel to organ) and temporal (from …
[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …
[HTML][HTML] Electro-mechanical whole-heart digital twins: a fully coupled multi-physics approach
T Gerach, S Schuler, J Fröhlich, L Lindner… - Mathematics, 2021 - mdpi.com
Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …
medicine and support clinical decision making by providing a powerful tool to understand …
[HTML][HTML] Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model
Anatomically accurate and biophysically detailed bidomain models of the human heart have
proven a powerful tool for gaining quantitative insight into the links between electrical …
proven a powerful tool for gaining quantitative insight into the links between electrical …
Calibration of ionic and cellular cardiac electrophysiology models
Cardiac electrophysiology models are among the most mature and well‐studied
mathematical models of biological systems. This maturity is bringing new challenges as …
mathematical models of biological systems. This maturity is bringing new challenges as …
Reconstruction of three-dimensional biventricular activation based on the 12-lead electrocardiogram via patient-specific modelling
Aims Non-invasive imaging of electrical activation requires high-density body surface
potential mapping. The nine electrodes of the 12-lead electrocardiogram (ECG) are …
potential mapping. The nine electrodes of the 12-lead electrocardiogram (ECG) are …
Towards personalized cardiology: multi-scale modeling of the failing heart
E Kayvanpour, T Mansi, F Sedaghat-Hamedani… - PLoS …, 2015 - journals.plos.org
Background Despite modern pharmacotherapy and advanced implantable cardiac devices,
overall prognosis and quality of life of HF patients remain poor. This is in part due to …
overall prognosis and quality of life of HF patients remain poor. This is in part due to …
Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions
L Cardone-Noott, A Bueno-Orovio, A Minchole… - EP …, 2016 - academic.oup.com
Aims To investigate how variability in activation sequence and passive conduction
properties translates into clinical variability in QRS biomarkers, and gain novel physiological …
properties translates into clinical variability in QRS biomarkers, and gain novel physiological …
MRI-based computational torso/biventricular multiscale models to investigate the impact of anatomical variability on the ECG QRS complex
Aims Patient-to-patient anatomical differences are an important source of variability in the
electrocardiogram, and they may compromise the identification of pathological …
electrocardiogram, and they may compromise the identification of pathological …