Development of myelinating glia: an overview

CD Cristobal, HK Lee - Glia, 2022 - Wiley Online Library
Myelin is essential to nervous system function, playing roles in saltatory conduction and
trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central …

Taking a bite out of spinal cord injury: do dental stem cells have the teeth for it?

J Bianco, P De Berdt, R Deumens… - Cellular and molecular life …, 2016 - Springer
Dental stem cells are an emerging star on a stage that is already quite populated. Recently,
there has been a lot of hype concerning these cells in dental therapies, especially in …

Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by …

M Tang, W Lin, J Zhang, Y Zhao, Y Li - Brain, Behavior, and Immunity, 2017 - Elsevier
Our previous work demonstrated that neuroinflammation evoked by triple repeated central
LPS challenges inhibited adult hippocampal neurogenesis that were correlated with the …

Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

L Zhou, CY Shao, YJ Xie, N Wang, SM Xu, BY Luo… - Elife, 2020 - elifesciences.org
Oligodendrocytes (OLs) myelinate axons and provide electrical insulation and trophic
support for neurons in the central nervous system (CNS). Platelet-derived growth factor …

Role of PDGF-A-activated ERK signaling mediated FAK-paxillin interaction in oligodendrocyte progenitor cell migration

J Singh, K Sharma, EE Frost, PP Pillai - Journal of Molecular Neuroscience, 2019 - Springer
Oligodendrocyte progenitor cells (OPCs) originate from the sub-ventricular zone of the
developing brain. They migrate and proliferate to occupy the white matter tracts of the central …

pERK1/2 peripheral recruitment and filopodia protrusion augment oligodendrocyte progenitor cell migration: combined effects of PDGF-A and fibronectin

A Tripathi, ZS Parikh, P Vora, EE Frost… - Cellular and molecular …, 2017 - Springer
Oligodendrocyte progenitor cell (OPC) migration is critical for effective myelination of the
central nervous system. Not only during normal myelination but also during remyelination …

MeCP2 overexpression inhibits proliferation, migration and invasion of C6 glioma by modulating ERK signaling and gene expression

K Sharma, J Singh, EE Frost, PP Pillai - Neuroscience Letters, 2018 - Elsevier
Abstract MethylCpG binding protein-2 (MeCP2) is an epigenetic regulator and essential for
brain development. MeCP2 mutations are associated with a spectrum of neuro …

Rapid and efficient differentiation of rodent neural stem cells into oligodendrocyte progenitor cells

S Li, J Zheng, L Chai, M Lin, R Zeng, J Lu… - Developmental …, 2019 - karger.com
Oligodendrocyte progenitor cells (OPCs) may have beneficial effects in cell replacement
therapy of neurodegenerative disease owing to their unique capability to differentiate into …

ERK1/2 signaling is essential for the chemoattraction exerted by human FGF2 and human anosmin‐1 on newborn rat and mouse OPCs via FGFR1

V Murcia‐Belmonte, EM Medina‐Rodríguez, A Bribián… - Glia, 2014 - Wiley Online Library
Signaling through fibroblast growth factor receptors (FGFRs) is essential for many cellular
processes including proliferation and migration, as well as differentiation events such as …

CXCL1 regulation of oligodendrocyte progenitor cell migration is independent of calcium signaling

P Vora, P Pillai, J Mustapha, C Kowal, S Shaffer… - Experimental …, 2012 - Elsevier
Cell migration is an indispensable aspect of tissue patterning during embryonic
development. Oligodendrocytes, the myelinating cells of the central nervous system, migrate …