The defining feature of the eukaryotic cell, the nucleus, is bounded by a double envelope.
This envelope and the nuclear pores within it play a critical role in separating the genome …

During early embryogenesis, as cells divide in the developing embryo, the size of
intracellular organelles generally decreases to scale with the decrease in overall cell size …

Eukaryote cell division features a chromosome compaction–decompaction cycle that is
synchronized with their physical and topological segregation. It has been proposed that …

All cellular proteins are synthesized by ribosomes, whose biogenesis in eukaryotes is a
complex multi-step process completed within minutes. Several chemical inhibitors of …

The nuclear envelope (NE) is a double-membrane structure consisting of inner and outer
membranes that spatially separate the nucleus from the cytoplasm, and its function is critical …

ABSTRACT CSL proteins [named after the homologs CBF1 (RBP-Jκ in mice), Suppressor of
Hairless and LAG-1] are conserved transcription factors found in animals and fungi. In the …

Mitotic fidelity is crucial for the faithful distribution of genetic information into the daughter
cells. Many fungal species, including the fission yeast Schizosaccharomyces pombe …

Cell division without growth results in progressive cell size reductions during early
embryonic development. How do the sizes of intracellular structures and organelles scale …

Fission yeast cells divide at a similar cell length with little variation about the mean. This is
thought to be the result of a control mechanism that senses size and corrects for any …

Within a eukaryotic cell, both lipid homeostasis and faithful cell cycle progression are
meticulously orchestrated. The fission yeast Schizosaccharomyces pombe provides a …