Biological properties of milk-derived extracellular vesicles and their physiological functions in infant

X Jiang, L You, Z Zhang, X Cui, H Zhong… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by all cells under pathological and physiological
conditions. EVs harbor various biomolecules, including protein, lipid, non-coding RNA …

Non-coding RNAs in human breast milk: A systematic review

L Tingö, E Ahlberg, L Johansson, SA Pedersen… - Frontiers in …, 2021 - frontiersin.org
Breast milk is the primary source of nutrition and hydration for the newborn infant but also
plays an important role in the child's first immune defense. Additionally, several breast milk …

Ecologies, synergies, and biological systems shaping human milk composition—a report from “Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN)” Working Group …

JT Smilowitz, LH Allen, DC Dallas… - The American journal of …, 2023 - Elsevier
Human milk is universally recognized as the preferred food for infants during the first 6 mo of
life because it provides not only essential and conditionally essential nutrients in necessary …

Extracellular vesicles in human milk

Y Hu, J Thaler, R Nieuwland - Pharmaceuticals, 2021 - mdpi.com
Milk supports the growth and development of infants. An increasing number of mostly recent
studies have demonstrated that milk contains a hitherto undescribed component called …

Regulation of adipogenesis by exosomal milk miRNA

MA Abbas, NN Al-Saigh, FG Saqallah - Reviews in Endocrine and …, 2023 - Springer
Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and
tissue distribution of milk exosomes was reported in newborn and adult humans and …

Potential epigenetic effects of human milk on infants' neurodevelopment

G Gialeli, O Panagopoulou, G Liosis, T Siahanidou - Nutrients, 2023 - mdpi.com
The advantages of human milk feeding, especially in preterm babies, are well recognized.
Infants' feeding with breast milk lowers the likelihood of developing a diverse range of non …

Shaping infant development from the inside out: Bioactive factors in human milk

SF Andres, B Scottoline, M Good - Seminars in perinatology, 2023 - Elsevier
Human breast milk is the optimal nutrition for all infants and is comprised of many bioactive
and immunomodulatory components. The components in human milk, such as probiotics …

Milk exosomal microRNAs: postnatal promoters of β cell proliferation but potential inducers of β cell de-differentiation in adult life

BC Melnik, G Schmitz - International Journal of Molecular Sciences, 2022 - mdpi.com
Pancreatic β cell expansion and functional maturation during the birth-to-weaning period is
driven by epigenetic programs primarily triggered by growth factors, hormones, and nutrients …

[HTML][HTML] Marine pollutant exposures and human milk extracellular vesicle-microRNAs in a mother-infant cohort from the Faroe Islands

A Kupsco, JJ Lee, D Prada, D Valvi, L Hu… - Environment …, 2022 - Elsevier
Abstract Background/Aims Early life exposures to marine contaminants can adversely
impact child health but modes of action are unclear. Human milk contains extracellular …

Current advances in technologies for single extracellular vesicle analysis and its clinical applications in cancer diagnosis

L Qiu, X Liu, L Zhu, L Luo, N Sun, R Pei - Biosensors, 2023 - mdpi.com
Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic
biomarkers for different cancers, due to their unique physiological and pathological …