Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Endocytosis of viruses and bacteria

P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins

AE Aplin, A Howe, SK Alahari, RL Juliano - Pharmacological reviews, 1998 - ASPET
Cell adhesion is critical for the genesis and maintenance of both three-dimensional structure
and normal function in tissues. The biochemical entities mediating cell adhesion are …

Listeria monocytogenes: a multifaceted model

M Hamon, H Bierne, P Cossart - Nature Reviews Microbiology, 2006 - nature.com
The opportunistic intracellular pathogen Listeria monocytogenes has become a paradigm
for the study of host–pathogen interactions and bacterial adaptation to mammalian hosts …

Exploitation of mammalian host cell functions by bacterial pathogens

BB Finlay, P Cossart - Science, 1997 - science.org
Interest in bacterial pathogenesis has recently increased because of antibiotic resistance,
the emergence of new pathogens and the resurgence of old ones, and the lack of effective …

A comprehensive review on intracellular delivery

D Morshedi Rad, M Alsadat Rad… - Advanced …, 2021 - Wiley Online Library
Intracellular delivery is considered an indispensable process for various studies, ranging
from medical applications (cell‐based therapy) to fundamental (genome‐editing) and …

Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells

E Veiga, P Cossart - Nature cell biology, 2005 - nature.com
The bacterial pathogen Listeria monocytogenes uses the surface protein InlB to invade a
variety of cell types,,. The interaction of InlB with the hepatocyte growth-factor receptor, Met …

Crystal structure of invasin: a bacterial integrin-binding protein

ZA Hamburger, MS Brown, RR Isberg, PJ Bjorkman - Science, 1999 - science.org
The Yersinia pseudotuberculosis invasin protein promotes bacterial entry by binding to host
cell integrins with higher affinity than natural substrates such as fibronectin. The 2.3 …

The opsonin MFG-E8 is a ligand for the αvβ5 integrin and triggers DOCK180-dependent Rac1 activation for the phagocytosis of apoptotic cells

S Akakura, S Singh, M Spataro, R Akakura… - Experimental cell …, 2004 - Elsevier
Opsonization of apoptotic cells facilitates recognition by phagocytes for the rapid clearance
of potentially inflammatory cellular material. The secreted glycoprotein Milk Fat Globule …

Adenovirus internalization and infection require dynamin

K Wang, S Huang, A Kapoor-Munshi… - Journal of …, 1998 - Am Soc Microbiol
The cell receptors that facilitate adenovirus internalization into cells have been identified;
however, the infectious pathway of virus entry has not been established. Adenovirus entry …