Drug-eluting stents and balloons—materials, structure designs, and coating techniques: a review

I Rykowska, I Nowak, R Nowak - Molecules, 2020 - mdpi.com
Controlled drug delivery is a matter of interest to numerous scientists from various domains,
as well as an essential issue for society as a whole. In the treatment of many diseases, it is …

Endovascular stent-induced alterations in host artery mechanical environments and their roles in stent restenosis and late thrombosis

J Wang, X Jin, Y Huang, X Ran, D Luo… - Regenerative …, 2018 - academic.oup.com
Cardiovascular stent restenosis remains a major challenge in interventional treatment of
cardiovascular occlusive disease. Although the changes in arterial mechanical environment …

Discovery of innovative therapeutics: today's realities and tomorrow's vision. 2. Pharma's challenges and their commitment to innovation

M Abou-Gharbia, WE Childers - Journal of medicinal chemistry, 2014 - ACS Publications
The pharmaceutical industry is facing enormous challenges, including reduced efficiency,
stagnant success rate, patent expirations for key drugs, fierce price competition from …

Bioresorbable polymer coated drug eluting stent: a model study

F Rossi, T Casalini, E Raffa, M Masi… - Molecular …, 2012 - ACS Publications
In drug eluting stent technologies, an increased demand for better control, higher reliability,
and enhanced performances of drug delivery systems emerged in the last years and thus …

Truncated YY1 interacts with BASP1 through a 339KLK341 motif in YY1 and suppresses vascular smooth muscle cell growth and intimal hyperplasia after vascular …

FS Santiago, Y Li, L Zhong, MJ Raftery… - Cardiovascular …, 2021 - academic.oup.com
Aims In-stent restenosis and late stent thrombosis are complications associated with the use
of metallic and drug-coated stents. Strategies that inhibit vascular smooth muscle cell (SMC) …

Loading and release of drugs from oxygen‐rich plasma polymer coatings

MJ Garcia‐Fernandez, L Martinez‐Calvo… - Plasma Processes …, 2012 - Wiley Online Library
Low‐pressure plasma‐polymerized ethylene film coatings rich in bonded oxygen groups (L‐
PPE: O) were deposited on poly (ethylene terephthalate; PET) in order to act as hosts for …

Efficacy and safety of biodegradable polymer biolimus-eluting stents versus durable polymer drug-eluting stents: a meta-analysis

Y Ye, H Xie, Y Zeng, X Zhao, Z Tian, S Zhang - PloS one, 2013 - journals.plos.org
Backgrounds Drug-eluting stents (DES) with biodegradable polymers have been developed
to address the risk of thrombosis associated with first-generation DES. We aimed to …

Inhibition of intimal thickening after vascular injury with a cocktail of vascular endothelial growth factor and cyclic Arg-Gly-Asp peptide

Y Li, LS McRobb, LM Khachigian - International Journal of Cardiology, 2016 - Elsevier
Background Percutaneous coronary intervention is widely used for the treatment of coronary
artery disease; however, significant challenges such as restenosis remain. Key to solving …

Design and evaluation of mixed self-assembled monolayers for a potential use in everolimus eluting coronary stents

A Mirmohseni, J Hosseini, M Shojaei… - Colloids and Surfaces B …, 2013 - Elsevier
Coronary artery disease (CAD) is still the leading cause of death throughout the world. Metal
stents are used to widen narrowed arteries. In addition, drug-eluting stents (DES) are widely …

Interleukin-1/toll-like receptor-induced nuclear factor kappa B signaling participates in intima hyperplasia after carotid artery balloon injury in goto-kakizaki rats: a …

X Zhang, Y Wang, W Hu, D Li, Z Zhou, D Pan, W Wu… - PLoS …, 2014 - journals.plos.org
The value of restenosis after percutaneous coronary intervention (PCI) is recognized
worldwide, especially for diabetic patients. Interleukin-1/Toll-like receptor (IL-1/TLR) …