Essential tremor pathology: neurodegeneration and reorganization of neuronal connections

ED Louis, PL Faust - Nature Reviews Neurology, 2020 - nature.com
Essential tremor (ET) is the most common tremor disorder globally and is characterized by
kinetic tremor of the upper limbs, although other clinical features can also occur. Postmortem …

Essential tremor: emerging views of a common disorder

J Benito-Leon, ED Louis - Nature clinical practice Neurology, 2006 - nature.com
Essential tremor (ET) is the most prevalent tremor disorder. ET has traditionally been viewed
as a monosymptomatic disorder characterized by a kinetic arm tremor, but this definition is …

Neuropathological changes in essential tremor: 33 cases compared with 21 controls

ED Louis, PL Faust, JPG Vonsattel, LS Honig, A Rajput… - Brain, 2007 - academic.oup.com
Despite its being one of the most commonly observed neurological disorders,
neuropathological studies of essential tremor (ET) are rare. There have been surprisingly …

Exploring the relationship between essential tremor and Parkinson's disease

J Shahed, J Jankovic - Parkinsonism & related disorders, 2007 - Elsevier
Although essential tremor (ET) and Parkinson's disease (PD) are considered distinct
disorders, there is overlap in some clinical features. In some PD patients, a long-standing …

Obesity and impaired cognitive functioning in the elderly: a population‐based cross‐sectional study (NEDICES)

J Benito‐León, AJ Mitchell… - European journal of …, 2013 - Wiley Online Library
Background and purpose Studies of high body mass index (BMI) and cognition in the elderly
have shown conflicting results. While some studies have shown a detrimental effect of high …

Risk of incident dementia in essential tremor: a population‐based study

F Bermejo‐Pareja, ED Louis… - … : official journal of the …, 2007 - Wiley Online Library
Essential tremor (ET) is a late-life neurological disease. Mild cognitive deficits as well as an
association with prevalent dementia have been reported in recent case–control studies. We …

Pathologic findings in prospectively ascertained essential tremor subjects

HA Shill, CH Adler, MN Sabbagh, DJ Connor… - Neurology, 2008 - AAN Enterprises
Objective: To assess pathologic changes in prospectively characterized subjects with
essential tremor (ET). Methods: Subjects enrolled in the Sun Health Research Institute Brain …

Tremor in the elderly: essential and aging‐related tremor

G Deuschl, I Petersen, D Lorenz… - Movement …, 2015 - Wiley Online Library
Background Isolated tremor in the elderly is commonly diagnosed as essential tremor (ET).
The prevalence of tremor increases steeply with increasing age, whereas hereditary tremor …

The roles of age and aging in essential tremor: an epidemiological perspective

ED Louis - Neuroepidemiology, 2019 - karger.com
Background: With an aging population, it behooves physicians and scientists to gain an
understanding of the intersections between aging and human disease. Here, the author …

Resistance, vulnerability and resilience: a review of the cognitive cerebellum in aging and neurodegenerative diseases

KJ Liang, ES Carlson - Neurobiology of learning and memory, 2020 - Elsevier
In the context of neurodegeneration and aging, the cerebellum is an enigma. Genetic
markers of cellular aging in cerebellum accumulate more slowly than in the rest of the brain …