[HTML][HTML] Recent Development in the Understanding of Molecular and Cellular Mechanisms Underlying the Etiopathogenesis of Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to
dementia and patient death. AD is characterized by intracellular neurofibrillary tangles …
dementia and patient death. AD is characterized by intracellular neurofibrillary tangles …
[HTML][HTML] Lipotoxicity-polarised macrophage-derived exosomes regulate mitochondrial fitness through Miro1-mediated mitophagy inhibition and contribute to type 2 …
JM Li, X Li, LWC Chan, R Hu, T Zheng, H Li, S Yang - Diabetologia, 2023 - Springer
Aims/hypothesis Insulin resistance is a major pathophysiological defect in type 2 diabetes
and obesity. Numerous experimental and clinical studies have provided evidence that …
and obesity. Numerous experimental and clinical studies have provided evidence that …
Alzheimer's disease in diabetic patients: a lipidomic prospect
BE Makki, S Rahman - Neuroscience, 2023 - Elsevier
Abstract Diabetes Mellitus (DM) and Alzheimer's disease (AD) have been two of the most
common chronic diseases affecting people worldwide. Type 2 DM (T2DM) is a metabolic …
common chronic diseases affecting people worldwide. Type 2 DM (T2DM) is a metabolic …
[HTML][HTML] The geroprotective drug candidate CMS121 alleviates diabetes, liver inflammation, and renal damage in db/db leptin receptor deficient mice
db/db mice, which lack leptin receptors and exhibit hyperphagia, show disturbances in
energy metabolism and are a model of obesity and type 2 diabetes. The geroneuroprotector …
energy metabolism and are a model of obesity and type 2 diabetes. The geroneuroprotector …
[HTML][HTML] Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa
W Boukhalfa, H Jmel, N Kheriji, I Gouiza… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Alzheimer's disease (AD) and Type 2 diabetes (T2D) are both age-associated
diseases. Identification of shared genes could help develop early diagnosis and preventive …
diseases. Identification of shared genes could help develop early diagnosis and preventive …
[HTML][HTML] The p66Shc Redox Protein and the Emerging Complications of Diabetes
G Biondi, N Marrano, A Borrelli, M Rella… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus is a chronic metabolic disease, the prevalence of which is constantly
increasing worldwide. It is often burdened by disabling comorbidities that reduce the quality …
increasing worldwide. It is often burdened by disabling comorbidities that reduce the quality …
[HTML][HTML] HDL levels modulate the impact of type 2 diabetes susceptibility alleles in older adults
Abstract Background Type 2 Diabetes (T2D) is influenced by genetic, environmental, and
ageing factors. Ageing pathways exacerbate metabolic diseases. This study aimed to …
ageing factors. Ageing pathways exacerbate metabolic diseases. This study aimed to …
[HTML][HTML] Insulin resistance as the molecular link between diabetes and Alzheimer's disease
MMI Abdalla - World Journal of Diabetes, 2024 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) and Alzheimer's disease (AD) are two major health concerns that
have seen a rising prevalence worldwide. Recent studies have indicated a possible link …
have seen a rising prevalence worldwide. Recent studies have indicated a possible link …
The Cellular Stability Hypothesis: Evidence of Ferroptosis and Accelerated Aging-Associated Diseases as Newly Identified Nutritional Pentadecanoic Acid (C15: 0) …
S Venn-Watson - Metabolites, 2024 - mdpi.com
Ferroptosis is a newly discovered form of cell death caused by the peroxidation of fragile
fatty acids in cell membranes, which combines with iron to increase reactive oxygen species …
fatty acids in cell membranes, which combines with iron to increase reactive oxygen species …
Improvement of Theaflavins on Glucose and Lipid Metabolism in Diabetes Mellitus
S Xu, Y Chen, Y Gong - Foods, 2024 - mdpi.com
In diabetes mellitus, disordered glucose and lipid metabolisms precipitate diverse
complications, including nonalcoholic fatty liver disease, contributing to a rising global …
complications, including nonalcoholic fatty liver disease, contributing to a rising global …