Background Children born to opioid-dependent mothers are at risk of adverse
neurodevelopment. The magnitude of this risk remains inconclusive. Objective To conduct a …

Converging evidence from clinical and preclinical studies suggests that fetal vulnerability to
adverse prenatal exposures increases the risk for neuropsychiatric diseases such as autism …

BACKGROUND: Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal
syndrome that can occur after intrauterine opioid exposure. Adverse neurobehavioral …

Background: Previous studies indicate an increased risk for neuropsychological difficulties
in young children prenatally exposed to opioids and polysubstances, but longitudinal …

Background The impact of prenatal opioid exposure on brain development remains poorly
understood. Methods We conducted a prospective study of term-born infants with and …

BACKGROUND AND OBJECTIVES: Neonatal abstinence syndrome (NAS) occurs after in
utero exposure to opioids, but outcomes after the postnatal period are unclear. Our …

Background Both animal and human studies have suggested that prenatal opioid exposure
may be detrimental to the developing fetal brain. However, results are somewhat conflicting …

Environmental exposures including toxins and nutrition may hamper the developing brain in
utero, limiting the brain's reserve capacity and increasing the risk for Alzheimer's disease …

Background While the health, social, and economic impacts of opioid addiction on adults
and their communities are well known, the impact of maternal opioid use on the fetus …

Coincident with the opioid epidemic in the United States has been a dramatic increase in the
number of children born with neonatal abstinence syndrome (NAS), a form of withdrawal …