Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Background Excessive opioid prescribing after surgery has contributed to the current opioid
crisis; however, the value of prescribing opioids at surgical discharge remains uncertain. We …

Postoperative pain is a common but often inadequately treated condition. Enhanced
recovery pathways (ERPs) are increasingly being utilized to standardize perioperative care …

Background The interscalene nerve block provides analgesia for shoulder surgery. To
extend block duration, provide adequate analgesia, and minimize opioid consumption, the …

Background As enhanced recovery programs (ERPs) have continued to evolve, the length of
hospitalization (LOS) following elective minimally invasive colorectal surgery has continued …

Background Opioids are frequently used in the postoperative period due to their analgesic
properties. While these drugs reduce nociceptive somatic, visceral, and neuropathic pain …

Introduction For close to a century opioid administration has been a standard of care to
complement anaesthesia during surgery. Considering the worldwide opioid epidemic, this …

Background and Objectives: The management of acute postoperative pain (APP) following
major abdominal surgery implies various analgetic strategies. Opioids lie at the core of every …

Background The purpose of this study was to study the effect of STING-IFN-I pathway on
incision induced postoperative pain in rats and its possible mechanisms. Methods The pain …

Importance The overprescription of opioids to surgical patients is recognized as an important
factor contributing to the opioid crisis. However, the value of prescribing opioid analgesia …