Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

[HTML][HTML] Phage therapy: a renewed approach to combat antibiotic-resistant bacteria

KE Kortright, BK Chan, JL Koff, PE Turner - Cell host & microbe, 2019 - cell.com
Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in
Western medicine. This stems from the rise in frequency of multi-drug-resistant bacterial …

Understanding bacterial biofilms: From definition to treatment strategies

A Zhao, J Sun, Y Liu - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
Bacterial biofilms are complex microbial communities encased in extracellular polymeric
substances. Their formation is a multi-step process. Biofilms are a significant problem in …

Fighting pathogenic bacteria on two fronts: phages and antibiotics as combined strategy

TL Tagliaferri, M Jansen, HP Horz - Frontiers in cellular and infection …, 2019 - frontiersin.org
With the emerging threat of infections caused by multidrug resistant bacteria, phages have
been reconsidered as an alternative for treating infections caused by tenacious pathogens …

Current challenges and future opportunities of phage therapy

DP Pires, AR Costa, G Pinto, L Meneses… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Phage therapy as an alternative or complementary strategy to prevent and control biofilm-related infections

DP Pires, LDR Melo, DV Boas, S Sillankorva… - Current opinion in …, 2017 - Elsevier
Highlights•Interaction of phages and biofilm cells depends on phage-host characteristics
and biofilm structure.•Biofilm features (eg matrix, cell metabolic state, resistant variants) …

[HTML][HTML] Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era

H Ling, X Lou, Q Luo, Z He, M Sun, J Sun - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Antibiotic resistance is one of the biggest threats to global health, as it can make the
treatment of bacterial infections in humans difficult owing to their high incidence rate …

[HTML][HTML] A combination therapy of Phages and Antibiotics: Two is better than one

X Li, Y He, Z Wang, J Wei, T Hu, J Si… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Emergence of antibiotic resistance presents a major setback to global health, and shortage
of antibiotic pipelines has created an urgent need for development of alternative therapeutic …

The mechanism of bacterial resistance and potential bacteriostatic strategies

F Zhang, W Cheng - Antibiotics, 2022 - mdpi.com
Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …