[HTML][HTML] Aspartic acid in health and disease

M Holeček - Nutrients, 2023 - mdpi.com
Aspartic acid exists in L-and D-isoforms (L-Asp and D-Asp). Most L-Asp is synthesized by
mitochondrial aspartate aminotransferase from oxaloacetate and glutamate acquired by …

d‐Amino acids in biological systems

S Du, M Wey, DW Armstrong - Chirality, 2023 - Wiley Online Library
Investigations on the occurrence and biochemical roles of free D‐amino acids and D‐amino
acid‐containing peptides and proteins in living systems have increased in frequency and …

[HTML][HTML] Innovative Artificial-Intelligence- Based Approach for the Biodegradation of Feather Keratin by Bacillus paramycoides, and Cytotoxicity of the Resulting Amino …

Z Moussa, DB Darwish, SS Alrdahe… - Frontiers in …, 2021 - frontiersin.org
The current study reported a new keratinolytic bacterium, which was characterized as
Bacillus paramycoides and identified by 16S rRNA, and the sequence was then deposited in …

[HTML][HTML] Evidence of the protective role of D-Aspartate in counteracting/preventing cadmium-induced oxidative stress in the rat testis

M Venditti, A Santillo, D Latino, MB Rhouma… - Ecotoxicology and …, 2023 - Elsevier
Cadmium (Cd), by producing oxidative stress and acting as an endocrine disruptor, is known
to cause severe testicular injury, documented by histological and biomolecular alterations …

d-Amino acids in mammalian endocrine tissues

G Chieffi Baccari, S Falvo, A Santillo… - Amino Acids, 2020 - Springer
Abstract d-Aspartate, d-serine and d-alanine are a regular occurrence in mammalian
endocrine tissues, though in amounts varying with the type of gland. The pituitary gland …

[HTML][HTML] New evidence on the role of d-aspartate metabolism in regulating brain and endocrine system physiology: From preclinical observations to clinical …

A Usiello, MM Di Fiore, A De Rosa, S Falvo… - International Journal of …, 2020 - mdpi.com
The endogenous amino acids serine and aspartate occur at high concentrations in free D-
form in mammalian organs, including the central nervous system and endocrine glands. D …

[HTML][HTML] D-Aspartate upregulates DAAM1 protein levels in the rat testis and induces its localization in spermatogonia nucleus

M Venditti, A Santillo, S Falvo, MM Di Fiore… - Biomolecules, 2020 - mdpi.com
Cell differentiation during spermatogenesis requires a proper actin dynamic, regulated by
several proteins, including formins. Disheveled-Associated-Activator of Morphogenesis1 …

[HTML][HTML] Relationships between Seminal Plasma Metabolites, Semen Characteristics and Sperm Kinetics in Donkey (Equus asinus)

MA Castiglione Morelli, A Ostuni, B Giangaspero… - Animals, 2021 - mdpi.com
Simple Summary A deeper knowledge of reproductive biology may be helpful in the donkey
to avoid the risk of extinction that some breeds are facing. The evaluation of metabolites in …

[HTML][HTML] d-aspartate and N-methyl-d-aspartate promote proliferative activity in mouse spermatocyte GC-2 cells

S Falvo, A Santillo, GC Baccari, F Cioffi… - Reproductive Biology, 2022 - Elsevier
Abstract D-Aspartate (D-Asp) and its methylated form N-methyl-d-aspartate (NMDA) promote
spermatogenesis by stimulating the biosynthesis of sex steroid hormones. d-Asp also …

[HTML][HTML] Preliminary investigation on the ameliorative role exerted by D-aspartic acid in counteracting ethane dimethane sulfonate (EDS) toxicity in the rat testis

M Venditti, MZ Romano, F Aniello, S Minucci - Animals, 2021 - mdpi.com
Simple Summary For proper fertility, the production of good-quality spermatozoa is essential.
Nowadays, many environmental pollutants affect the spermatogenetic process, at different …