Sarcopenia

AJ Cruz-Jentoft, AA Sayer - The Lancet, 2019 - thelancet.com
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the
accelerated loss of muscle mass and function that is associated with increased adverse …

Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms

FW Booth, CK Roberts, JP Thyfault… - Physiological …, 2017 - journals.physiology.org
This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

Sarcopenia: prevalence, associated factors, and the risk of mortality and disability in Japanese older adults

A Kitamura, S Seino, T Abe, Y Nofuji… - Journal of cachexia …, 2021 - Wiley Online Library
Background There is limited evidence on sarcopenia in Asian populations. This study aimed
to clarify the prevalence, associated factors, and the magnitude of association with mortality …

Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank …

CA Celis-Morales, P Welsh, DM Lyall, L Steell… - bmj, 2018 - bmj.com
Objective To investigate the association of grip strength with disease specific incidence and
mortality and whether grip strength enhances the prediction ability of an established office …

The genetics of human ageing

D Melzer, LC Pilling, L Ferrucci - Nature Reviews Genetics, 2020 - nature.com
The past two centuries have witnessed an unprecedented rise in human life expectancy.
Sustaining longer lives with reduced periods of disability will require an understanding of the …

Short physical performance battery and all-cause mortality: systematic review and meta-analysis

R Pavasini, J Guralnik, JC Brown, M di Bari, M Cesari… - BMC medicine, 2016 - Springer
Abstract Background The Short Physical Performance Battery (SPPB) is a well-established
tool to assess lower extremity physical performance status. Its predictive ability for all-cause …

[HTML][HTML] Stimuli and sensors that initiate skeletal muscle hypertrophy following resistance exercise

H Wackerhage, BJ Schoenfeld… - Journal of applied …, 2019 - journals.physiology.org
One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that
occurs in response to resistance exercise. A large body of work shows that a mammalian …

Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million …

A García-Hermoso, I Cavero-Redondo… - Archives of physical …, 2018 - Elsevier
Objectives The aims of the present systematic review and meta-analysis were to determine
the relationship between muscular strength and all-cause mortality risk and to examine the …

Musculoskeletal health conditions represent a global threat to healthy aging: a report for the 2015 World Health Organization world report on ageing and health

AM Briggs, MJ Cross, DG Hoy… - The …, 2016 - academic.oup.com
Persistent pain, impaired mobility and function, and reduced quality of life and mental well-
being are the most common experiences associated with musculoskeletal conditions, of …

The structure and predictive value of intrinsic capacity in a longitudinal study of ageing

JR Beard, AT Jotheeswaran, M Cesari… - BMJ open, 2019 - bmjopen.bmj.com
Objectives To assess the validity of the WHO concept of intrinsic capacity in a longitudinal
study of ageing; to identify whether this overall measure disaggregated into biologically …