Rationale: Colorectal cancer (CRC) is a common malignant tumor of the digestive system.
However, the efficacy of surgery and chemotherapy is limited. Ferroptosis is an iron-and …

Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …

Cutaneous squamous cell carcinoma (cSCC) is a common type of neoplasia, representing a
terrible burden on patients' life and clinical management. Although it seldom metastasizes …

Emerging evidence suggests that the cancer stem cells (CSCs) are key culprits of cancer
metastasis and drug resistance. Understanding mechanisms regulating the critical …

Abstract Long noncoding RNAs (LncRNAs), including MALAT1, are critical regulators of
tumor development. However, the roles and molecular mechanisms of LncRNAs in …

MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …

Programmed cell death-ligand 1 (PD-L1) is a glycoprotein that is expressed on the cell
surface of both hematopoietic and nonhematopoietic cells. PD-L1 play a role in the immune …

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer,
originating from keratinocytes of the spinous layer. Numerous risk factors have been …

Skin, the largest organ of human body, is vital for the existence and survival of human
beings. Further, developmental and physiological mechanisms associated with cutaneous …

Abstract Background MicroRNA-125b (miR-125b) is downregulated in human cutaneous
squamous cell carcinoma (CSCC). However, its function in CSCC has yet to be extensively …