[HTML][HTML] Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells
R Wei, Y Zhao, J Wang, X Yang, S Li… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Rationale: Colorectal cancer (CRC) is a common malignant tumor of the digestive system.
However, the efficacy of surgery and chemotherapy is limited. Ferroptosis is an iron-and …
However, the efficacy of surgery and chemotherapy is limited. Ferroptosis is an iron-and …
[HTML][HTML] MicroRNA dysregulation in cutaneous squamous cell carcinoma
N García-Sancha, R Corchado-Cobos… - International journal of …, 2019 - mdpi.com
Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …
[HTML][HTML] Deciphering the molecular landscape of cutaneous squamous cell carcinoma for better diagnosis and treatment
Cutaneous squamous cell carcinoma (cSCC) is a common type of neoplasia, representing a
terrible burden on patients' life and clinical management. Although it seldom metastasizes …
terrible burden on patients' life and clinical management. Although it seldom metastasizes …
[HTML][HTML] miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma
S Yuan, P Zhang, L Wen, S Jia, Y Wu, Z Zhang, L Guan… - Oncogene, 2021 - nature.com
Emerging evidence suggests that the cancer stem cells (CSCs) are key culprits of cancer
metastasis and drug resistance. Understanding mechanisms regulating the critical …
metastasis and drug resistance. Understanding mechanisms regulating the critical …
[HTML][HTML] MALAT1-KTN1-EGFR regulatory axis promotes the development of cutaneous squamous cell carcinoma
Y Zhang, L Gao, S Ma, J Ma, Y Wang, S Li… - Cell Death & …, 2019 - nature.com
Abstract Long noncoding RNAs (LncRNAs), including MALAT1, are critical regulators of
tumor development. However, the roles and molecular mechanisms of LncRNAs in …
tumor development. However, the roles and molecular mechanisms of LncRNAs in …
[HTML][HTML] miRNA in molecular diagnostics
MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …
How microRNAs affect the PD-L1 and its synthetic pathway in cancer
GR Danbaran, S Aslani, N Sharafkandi… - International …, 2020 - Elsevier
Programmed cell death-ligand 1 (PD-L1) is a glycoprotein that is expressed on the cell
surface of both hematopoietic and nonhematopoietic cells. PD-L1 play a role in the immune …
surface of both hematopoietic and nonhematopoietic cells. PD-L1 play a role in the immune …
[HTML][HTML] Update on the molecular pathology of cutaneous squamous cell carcinoma
EC Cozma, LM Banciu, C Soare… - International Journal of …, 2023 - mdpi.com
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer,
originating from keratinocytes of the spinous layer. Numerous risk factors have been …
originating from keratinocytes of the spinous layer. Numerous risk factors have been …
[HTML][HTML] Role of non-coding RNAs in the progression and resistance of cutaneous malignancies and autoimmune diseases
Skin, the largest organ of human body, is vital for the existence and survival of human
beings. Further, developmental and physiological mechanisms associated with cutaneous …
beings. Further, developmental and physiological mechanisms associated with cutaneous …
[HTML][HTML] MicroRNA-125b exerts antitumor functions in cutaneous squamous cell carcinoma by targeting the STAT3 pathway
K Tian, W Liu, J Zhang, X Fan, J Liu, N Zhao… - Cellular & molecular …, 2020 - Springer
Abstract Background MicroRNA-125b (miR-125b) is downregulated in human cutaneous
squamous cell carcinoma (CSCC). However, its function in CSCC has yet to be extensively …
squamous cell carcinoma (CSCC). However, its function in CSCC has yet to be extensively …