The dimensionality of cytometry data has strongly increased in the last decade, and in many
situations the traditional manual downstream analysis becomes insufficient. The field is …

Technology development in biological research often aims to either increase the number of
cellular features that can be surveyed simultaneously or enhance the resolution at which …

Scanpy is a scalable toolkit for analyzing single-cell gene expression data. It includes
methods for preprocessing, visualization, clustering, pseudotime and trajectory inference …

Epidemiological data suggest that early life exposures are key determinants of immune-
mediated disease later in life. Young children are also particularly susceptible to infections …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Microglia, the specialized innate immune cells of the CNS, play crucial roles in neural
development and function. Different phenotypes and functions have been ascribed to rodent …

Accurate and comprehensive extraction of information from high-dimensional single cell
datasets necessitates faithful visualizations to assess biological populations. A state-of-the …

Cells, the basic units of biological structure and function, vary broadly in type and state.
Single-cell genomics can characterize cell identity and function, but limitations of ease and …

Single-cell genomics has now made it possible to create a comprehensive atlas of human
cells. At the same time, it has reopened definitions of a cell's identity and of the ways in …

Innate lymphoid cells (ILCs) are critical modulators of mucosal immunity, inflammation, and
tissue homeostasis, but their full spectrum of cellular states and regulatory landscapes …