Ischemic stroke (IS) has become the second leading cause of morbidity and mortality
worldwide, and the prevention of IS should be given high priority. Recent studies have …

Oxidative stress, an imbalance between reactive oxygen species and antioxidants, has been
seen in the pathological states of many disorders such as ischemic diseases and cancers …

Background and purpose A major gap in the field of ischemic preconditioning (IPC) is
whether or not long-lasting neuroprotection can be achieved. Moreover, the specific …

Hypoxia is a major stressor and a prominent feature of pathological conditions, such as
bacterial infections, inflammation, wounds, and cardiovascular defects. In this study, we …

Neonatal hypoxic-ischemic encephalopathy (HIE) is considered a major cause of death and
long-term neurological injury in newborns. Studies have demonstrated that oxidative stress …

Brain ischemic preconditioning (IPC) with mild ischemic episodes is well known to protect
the brain against subsequent ischemic challenges. However, the underlying mechanisms …

Memory decline is characteristic of aging and age-related neurodegenerative disorders.
This study was designed to investigate the protective effect of hyperbaric oxygen (HBO) …

Neonatal hypoxic-ischemic (HI) brain injury can lead to mortality and severe long-term
disabilities including cerebral palsy and brain injury. However, the treatment options for …

To investigate the potential neuroprotection of oxymatrine in hypoxic-ischemic injury in rat's
brain and the associated underlying mechanisms, modified neurological severity scores …

Hypoxemia is a common complication of the diseases associated with the central nervous
system, and neurons are highly sensitive to the availability of oxygen. Neuroplasticity is an …