This review summarizes knowledge concerning a ubiquitous plasma transmembraneprotein
family that mediates nucleobase or ascorbate secondary active transport (NAT). We show …

Early genetic and physiological work in bacteria and fungi has suggested the presence of
highly specific nucleobase transport systems. Similar transport systems are now known to …

Cell nutrition, detoxification, signalling, homeostasis and response to drugs, processes
related to cell growth, differentiation and survival are all mediated by plasma membrane …

Transporters are ubiquitous proteins mediating the translocation of solutes across cell
membranes, a biological process involved in nutrition, signaling, neurotransmission, cell …

In this work we unmask a novel downregulation mechanism of the uric acid/xanthine
transporter UapA, the prototype member of the ubiquitous Nucleobase‐Ascorbate …

Efficient transporters are necessary for high concentration and purity of desired products
during industrial production. In this study, we explored the mechanism of substrate transport …

Transporters are transmembrane proteins mediating the selective uptake or efflux of solutes,
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …

Solute carriers from the SLC4, SLC23, and SLC26 families are involved in pH regulation,
vitamin C transport and ion homeostasis. While these families do not share any obvious …

Transporters are essential transmembrane proteins that mediate the selective translocation
of solutes, ions or drugs across biological membranes. Their function is related to cell …

Transport assays allow the direct kinetic analysis of a specific transporter by measuring
apparent K m and V max values, and permit the characterization of substrate specificity …