Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimising the use of
biologics, and in particular anti-tumour necrosis factor (anti-TNF) therapy, in inflammatory …

The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease …

Importance Proactive therapeutic drug monitoring (TDM), defined as individualized drug
dosing based on scheduled monitoring of serum drug levels, has been proposed as an …

The management of patients with moderate to severe inflammatory bowel disease was
transformed with the arrival of anti–tumor necrosis factor (TNF) therapy. Nevertheless, a …

Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease deriving
from the hair follicles. The formation of inflammatory nodules, abscesses, fistulas, and sinus …

Colorectal cancer (CRC) is the third most diagnosed malignancy and a major leading cause
of cancer-related deaths worldwide. Despite advances in therapeutic regimens, the number …

Biologic drugs have greatly improved treatment outcomes of inflammatory joint diseases, but
a substantial proportion of patients either do not respond to treatment or lose response over …

Infliximab and adalimumab are monoclonal antibodies against tumor necrosis factor (anti-
TNF) used to manage inflammatory bowel disease (IBD). Therapeutic Drug Monitoring …

Biological medicines have improved patients' outcomes, but their high costs may limit
access. Biosimilars, alternatives that have demonstrated high similarity in terms of quality …

Thiopurines have been a cornerstone in the treatment of inflammatory bowel disease (IBD).
Although they have been used for more than 50 years, there are still some unsolved issues …