In his seminal work, 1 Rolf Huisgen defined 1, 3-dipolar cycloadditions as “1, 3-Dipole, abc,
must be defined, such that atom a posseses an electron sextet, that is, an incomplete …

Chiral phosphoric acids (CPAs) have emerged as powerful organocatalysts for asymmetric
reactions, and applications of computational quantum chemistry have revealed important …

Can green chemistry be the right reading key to let organocatalyst design take a step
forward towards sustainable catalysis? What if the intriguing chemistry promoted by more …

Azomethine imines are considered 1, 3-dipoles of the aza-allyl type which are transient
intermediates and should be generated in situ but can also be stable and isolable …

Abstract Carbon–hydrogen (C–H) and carbon–carbon (C–C) bonds are the main
constituents of organic matter. Recent advances in C–H functionalization technology have …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …

Rearrangement reactions have attracted considerable interest over the past decades due to
their high bond-forming efficiency and atom economy in the construction of complex organic …

An unprecedented ligand-controlled regiodivergent Cu (I)-catalyzed asymmetric
intermolecular (3+ 2) cycloaddition reaction of α-substituted iminoesters with β-fluoromethyl …

A novel photocatalytic hydrazonyl radical-mediated radical cyclization/allylation cascade
reaction of β, γ-unsaturated hydrazones is developed using allyl sulfones and Morita–Baylis …

N-Triflylphosphoramides (NTPA), have become increasingly popular catalysts in the
development of enantioselective transformations as they are stronger Brønsted acids than …