Mining genomes to illuminate the specialized chemistry of life

MH Medema, T de Rond, BS Moore - Nature Reviews Genetics, 2021 - nature.com
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …

[HTML][HTML] The structure and function of major plant metabolite modifications

S Wang, S Alseekh, AR Fernie, J Luo - Molecular Plant, 2019 - cell.com
Plants produce a myriad of structurally and functionally diverse metabolites that play many
different roles in plant growth and development and in plant response to continually …

A specialized metabolic network selectively modulates Arabidopsis root microbiota

AC Huang, T Jiang, YX Liu, YC Bai, J Reed, B Qu… - Science, 2019 - science.org
INTRODUCTION Specialized metabolism is a feature of plant evolution and adaption. Plant-
specialized metabolites have ecological functions, mediating interactions between plants …

[HTML][HTML] Rewiring of the fruit metabolome in tomato breeding

G Zhu, S Wang, Z Huang, S Zhang, Q Liao, C Zhang… - Cell, 2018 - cell.com
Humans heavily rely on dozens of domesticated plant species that have been further
improved through intensive breeding. To evaluate how breeding changed the tomato fruit …

[HTML][HTML] The Taxus genome provides insights into paclitaxel biosynthesis

X Xiong, J Gou, Q Liao, Y Li, Q Zhou, G Bi, C Li, R Du… - Nature Plants, 2021 - nature.com
The ancient gymnosperm genus Taxus is the exclusive source of the anticancer drug
paclitaxel, yet no reference genome sequences are available for comprehensively …

[HTML][HTML] Resequencing of 414 cultivated and wild watermelon accessions identifies selection for fruit quality traits

S Guo, S Zhao, H Sun, X Wang, S Wu, T Lin, Y Ren… - Nature …, 2019 - nature.com
Fruit characteristics of sweet watermelon are largely the result of human selection. Here we
report an improved watermelon reference genome and whole-genome resequencing of 414 …

[HTML][HTML] The integrated genomics of crop domestication and breeding

X Huang, S Huang, B Han, J Li - Cell, 2022 - cell.com
As a major event in human civilization, wild plants were successfully domesticated to be
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …

Exploring the diversity of plant metabolism

C Fang, AR Fernie, J Luo - Trends in Plant Science, 2019 - cell.com
Plants produce a huge array of metabolites, far more than those produced by most other
organisms. Unraveling this diversity and its underlying genetic variation has attracted …

Origin and domestication of Cucurbitaceae crops: insights from phylogenies, genomics and archaeology

G Chomicki, H Schaefer, SS Renner - New Phytologist, 2020 - Wiley Online Library
Some of the World's most valuable crops, including watermelon, honey melon, cucumber,
squash, zucchini and pumpkin, belong to the family Cucurbitaceae. We review insights on …

A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

G Zhao, Q Lian, Z Zhang, Q Fu, Y He, S Ma… - Nature Genetics, 2019 - nature.com
Melon is an economically important fruit crop that has been cultivated for thousands of years;
however, the genetic basis and history of its domestication still remain largely unknown …