The transdermal route of drugs has received increased attention in recent years due to
numerous advantages over the oral and injectable routes, such as avoidance of the hepatic …

In recent years, significant progress has been made in transdermal drug delivery systems,
but there is still a search for enhancers that can improve the absorption of active substances …

Abstract Three-dimensional (3D) cell-printing has been emerging as a promising technology
with which to build up human skin models by enabling rapid and versatile design. Despite …

Cutaneous wound healing in the pig is frequently used as a model for human cutaneous
wound healing. In this review, we examine the appropriateness of this model for studying …

In vitro diffusive models are an important tool to screen the penetration ability of active
ingredients in various formulations. A reliable assessment of skin penetration enhancing …

Models of the outer epithelia of the human body-namely the skin, the intestine and the lung-
have found valid applications in both research and industrial settings as attractive …

Three-dimensional (3D) printed skin substitutes have great potential for wound healing.
However, current 3D printed skin models are limited in simulating heterogeneity and …

A novel microemulsion was developed and characterized for topical delivery of Dencichine
(Den). Two imidazaolium ionic liquid, 1-hydroxyethyl-3-methylimidazolium chloride ([HOEIM] …

Griseofulvin (GRF) is an important antifungal drug with low bioavailability and, for this
reason, a topical formulation with a targeted action and minimal systemic effects, appears to …

For an improved understanding of the relevant particle features for cutaneous use, we
studied the effect of the surface charge of acrylic nanocapsules (around 150 nm) and the …