The temporomandibular joint (TMJ) is a specialized synovial joint that is crucial for the
movement and function of the jaw. TMJ osteoarthritis (TMJ OA) is the result of disc …

Background The success of stem cell therapy for knee osteoarthritis (KOA) in preclinical
animal models has accelerated the pace of clinical translation. However, it remains …

Background: Intra-articular injection of autologous culture-expanded adipose-derived
mesenchymal stem cells (ADMSCs) has introduced a promising treatment option for knee …

Background Intra-articular injection of mesenchymal stromal cells (MSCs) with
immunomodulatory features and their paracrine secretion of regenerative factors proposed a …

Knee osteoarthritis, a widespread degenerative condition, impacts a younger population
and leads to high disability rates. Nature often provides solutions for aging and disease …

Abstract Purpose Mesenchymal stem cells (MSCs) present a valuable treatment option for
knee osteoarthritis with promising results. The purpose of the present study was to …

Objective Osteoarthritis (OA) displays features of systemic and local inflammation,
suggesting that DMARDs used in rheumatoid arthritis could potentially also be effective in …

Purpose To evaluate the safety and efficacy of platelet-rich plasma (PRP) intra-articular
injective treatments for ankle osteoarthritis (OA). Methods A systematic literature search was …

Adipose tissue-derived cell-based injectable therapies have been demonstrated to have
disease-modifying effects on joint tissues in preclinical studies on animal osteoarthritis (OA) …

Background: Enzymatic digestion of extracellular matrix (ECM) from lipoaspirate is the
conventional form of harvesting stromal vascular fraction (SVF) called enzymatically …