[HTML][HTML] Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region

KP Wong, M Wardak, W Shao, M Dahlbom… - European journal of …, 2010 - Springer
Purpose Subcortical white matter is known to be relatively unaffected by amyloid deposition
in Alzheimer's disease (AD). We investigated the use of subcortical white matter as a …

FDDNP binding using MR derived cortical surface maps

HD Protas, SC Huang, V Kepe, K Hayashi, A Klunder… - Neuroimage, 2010 - Elsevier
OBJECTIVES: To assess quantitatively the cortical pattern profile of regional FDDNP binding
to beta-amyloid and neurofibrillary tangles on MR derived cortical maps, FDDNP PET …

Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET

HD Protas, V Kepe, KM Hayashi, AD Klunder… - Neuroimage, 2012 - Elsevier
OBJECTIVES: A cross-sectional study to establish whether a subject's cognitive state can be
predicted based on regional values obtained from brain cortical maps of FDDNP Distribution …

Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F] FDDNP PET determinations

KP Wong, V Kepe, M Dahlbom, N Satyamurthy… - NeuroImage, 2012 - Elsevier
Logan graphical analysis with cerebellum as reference region has been widely used for the
estimation of the distribution volume ratio (DVR) of [18F] FDDNP as a measure of amyloid …

Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer′ s Disease Patients

MQ Wilks, H Protas, M Wardak, V Kepe… - International Journal …, 2012 - Wiley Online Library
We evaluate an automated approach to the cortical surface mapping (CSM) method of VOI
analysis in PET. Although CSM has been previously shown to be successful, the process …

A bootstrap method for identifying image regions affected by intra-scan body movement during a PET/CT scan

SC Huang, H Ye, M Wardak, KP Wong… - 2011 IEEE Nuclear …, 2011 - ieeexplore.ieee.org
Intra-scan body movement (IBM) during a PET/CT study can degrade the image quality in
subtle ways that are not easy for physicians to detect and can thus affect the diagnostic …

Evaluation of two graphical approaches for regional analysis and parametric mapping of dynamic [18F]FDDNP PET studies

KP Wong, SC Huang, V Kepe… - 2009 IEEE Nuclear …, 2009 - ieeexplore.ieee.org
Positron emission tomography (PET) with 2-(1-{6-[(2-[18 F] fluoroethyl)(methyl) amino]-2-
naphthyl} ethylidene) malo-nonitrile ([18 F] FDDNP) has been used for in vivo imaging of …