CRISPR-based precision molecular diagnostics for disease detection and surveillance

A Kulkarni, S Tanga, A Karmakar, A Hota… - ACS Applied Bio …, 2023 - ACS Publications
Sensitive, rapid, and portable molecular diagnostics is the future of disease surveillance,
containment, and therapy. The recent SARS-CoV-2 pandemic has reminded us of the …

[HTML][HTML] An update on the application of CRISPR technology in clinical practice

F Morshedzadeh, M Ghanei, M Lotfi, M Ghasemi… - Molecular …, 2024 - Springer
The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …

Highly sensitive and rapid detection of SARS‐CoV‐2 via a portable CRISPR‐Cas13a‐based lateral flow assay

H Liu, S Chang, S Chen, Y Du, H Wang… - Journal of Medical …, 2022 - Wiley Online Library
To rapidly identify individuals infected with severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) and control the spread of coronavirus disease (COVID‐19), there is an …

[HTML][HTML] Applying targeted gene hybridization capture to viruses with a focus to SARS-CoV-2

A Ceballos-Garzon, S Comtet-Marre, P Peyret - Virus Research, 2024 - Elsevier
Although next-generation sequencing technologies are advancing rapidly, many research
topics often require selective sequencing of genomic regions of interest. In addition …

Development and validation of a CRISPR/Cas12a-based platform for rapid and sensitive detection of the large yellow croaker iridovirus

C Zhang, Z Tao, H Ye, P Wang, M Jiang, K Benard… - Aquaculture, 2024 - Elsevier
Large yellow croaker iridovirus (LYCIV) poses a growing threat to large yellow croaker
(Larimichthys crocea) aquaculture, requiring early diagnosis for effective prevention and …

[HTML][HTML] Evolution and Impact of Nucleic Acid Amplification Test (NAAT) for Diagnosis of Coronavirus Disease

SF Khan, P Rathod, VK Gupta, PB Khedekar… - Analytical …, 2024 - ACS Publications
Severe acute respiratory syndrome Coronavirus 2, or SARS-CoV-2, previously known as
2019-CoV, is an encapsulated, positive-sense, single-stranded genomic RNA virus (+ …

[HTML][HTML] Validation of rapid and economic colorimetric nanoparticle assay for SARS-CoV-2 RNA detection in saliva and nasopharyngeal swabs

M Armesto, M Charconnet, JM Marimón… - Biosensors, 2023 - mdpi.com
Even with the widespread uptake of vaccines, the SARS-CoV-2-induced COVID-19
pandemic continues to overwhelm many healthcare systems worldwide. Consequently …

Targeting host calcium channels and viroporins: a promising strategy for SARS-CoV-2 therapy

M Fani, M Moossavi, H Bakhshi, AN Jahrodi… - Future …, 2023 - Taylor & Francis
Despite passing the pandemic phase of the COVID-19, researchers are still investigating
various drugs. Previous evidence suggests that blocking the calcium channels may be a …

Recent Advances and Practical Applications of CRISPR/Cas Technology in Clinical Trial of Cancer and Infectious Diseases: A Comprehensive Review

Z Haji Mehdi Nouri, H Poormazaheri… - Micro Nano Bio …, 2024 - mnba-journal.com
CRISPR/Cas technology is a powerful technique for gene editing, with impressive accuracy
and efficiency. It has the potential to revolutionize the treatment of genetic diseases and …

Focused ion beam-fabricated nanorod substrate for label-free surface-enhanced Raman spectroscopy and enabling dual virus detection

H Lee, JD Liao, HP Tsai, H Wang, J Sitjar - Talanta, 2024 - Elsevier
The COVID-19 pandemic presents global challenges, notably with co-infections in
respiratory tract involving SARS-CoV-2 variants and influenza strains. Detecting multiple …