[HTML][HTML] Genetics of sinoatrial node function and heart rate disorders

LE van der Maarel, AV Postma… - Disease models & …, 2023 - journals.biologists.com
The sinoatrial node (SAN) is the primary pacemaker of the mammalian heart, initiating its
electrical activation and ensuring that the heart's functional cardiac output meets …

[HTML][HTML] Modeling human cardiac arrhythmias: insights from zebrafish

S Gauvrit, J Bossaer, J Lee, MM Collins - Journal of Cardiovascular …, 2022 - mdpi.com
Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and
is described as one of the most important future public health challenges. Therefore …

Quantification of left atrial fibrosis by 3D late gadolinium-enhanced cardiac magnetic resonance imaging in patients with atrial fibrillation: impact of different analysis …

LHGA Hopman, P Bhagirath, MJ Mulder… - European Heart …, 2022 - academic.oup.com
Aims Various methods and post-processing software packages have been developed to
quantify left atrial (LA) fibrosis using 3D late gadolinium-enhancement cardiac magnetic …

Impact of diagnosis‐to‐ablation time on clinical outcomes in patients with early‐onset atrial fibrillation

L Zhou, Y Kong, C Sang, S Xia, C Jiang, L He… - Clinical …, 2024 - Wiley Online Library
Background Evidence was lacking for the early choice of radiofrequency ablation (RFA)
among patients with early‐onset atrial fibrillation (AF). Hypothesis This study aimed to …

[HTML][HTML] Cardiomyopathy prevalence exceeds 30% in individuals with TTN variants and early atrial fibrillation

KMS Barrett, ET Cirulli, A Bolze, C Rowan… - Genetics in …, 2023 - Elsevier
Purpose TTN truncating variants (TTNtvs) represent the largest known genetic cause of
dilated cardiomyopathies (DCMs), however their penetrance for DCM in general populations …

Genetic findings in patients with primary fibrotic atrial cardiomyopathy

Y Zhu, J Shi, B Zheng, H Liu, C Li, W Ju, D Wang… - European Journal of …, 2022 - Elsevier
Primary fibrotic atrial cardiomyopathy (PF-ACM) is a novel type of cardiomyopathy
characterized by primary atrial fibrosis with arrhythmogenicity and increased stroke risk …

Genetically based atrial fibrillation: Current considerations for diagnosis and management

AV Pensa, JR Baman, MJ Puckelwartz… - Journal of …, 2022 - Wiley Online Library
Atrial fibrillation (AF) is the most common atrial arrhythmia and is subcategorized into
numerous clinical phenotypes. Given its heterogeneity, investigations into the genetic …

[HTML][HTML] Genetic Characterization of Dilated Cardiomyopathy in Romanian Adult Patients

OR Voinescu, BI Ionescu, S Militaru, AS Afana… - International Journal of …, 2024 - mdpi.com
Dilated cardiomyopathy (DCM) represents a group of disorders affecting the structure and
function of the heart muscle, leading to a high risk of heart failure and sudden cardiac death …

[HTML][HTML] Genetic Basis of Early Onset Atrial Fibrillation in Patients without Risk Factors

I Rudaka, B Vilne, J Isakova, O Kalejs, L Gailite… - Journal of …, 2023 - mdpi.com
Background: Atrial fibrillation (AF) is the most common arrhythmia and typically occurs in
elderly patients with other cardiovascular and extracardiac diseases. However, up to 15% of …

[HTML][HTML] Screening, diagnosis and management of atrial fibrillation in cancer patients: current evidence and future perspectives

P Goncalves-Teixeira, T Costa, I Fragoso… - Arquivos Brasileiros …, 2022 - SciELO Brasil
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general
population, carrying a high morbimortality burden, and this also holds true in cancer …