A primary goal in organ transplantation is the prevention or effective treatment of infection,
the most common life-threatening complication of long-term immunosuppressive therapy …

Cytomegalovirus (CMV) infection is one of the most important infectious complications of
solid-organ transplantation, and is also responsible for serious, life-threatening diseases in …

Cytomegalovirus (CMV) is recognized as the most common congenital viral infection in
humans and an important cause of morbidity and mortality in immunocompromised hosts …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

The pharmacokinetics of an orally administered valine ester of ganciclovir (GCV),
valganciclovir (VGC), were studied. These were compared to the pharmacokinetics of oral …

Invasive aspergillosis occurred in 26 liver transplant recipients since 1990 at five liver
transplant centers. The median time to onset was 17 days after transplantation. Twenty …

Human cytomegalovirus (HCMV) infection plays an important role in transplant patients. Its
impact is both direct and indirect. This review focuses on new aspects of HCMV (re) …

Ischemic cholangiopathy can be defined as a focal or extensive damage to the bile ducts
due to impaired blood supply [1]. This entity may be observed in various circumstances …

ABSTRACT A quantitative real-time PCR assay was developed to measure human
cytomegalovirus (HCMV) DNA load in peripheral blood leukocytes (PBLs). The HCMV DNA …

Whether preemptive therapy or universal prophylaxis with ganciclovir is the optimal
approach against cytomegalovirus (CMV) remains unresolved. Controversy abounds with …