Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …

The skin is the largest organ of the human body and the one mostly exposed to outdoor
contaminants. To evaluate the biological mechanisms underlying skin damage caused by …

The incidence of renal cell carcinoma (RCC) is increasing worldwide with an approximate
20% mortality rate. The challenge in RCC is the therapy-resistance. Cancer resistance to …

Alzheimer's disease (AD) progressively inflicts impairment of synaptic functions with notable
deposition of amyloid-β (Aβ) as senile plaques within the extracellular space of the brain …

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

While cisplatin is a first-line chemotherapeutic drug commonly used to treat patients with oral
squamous cell carcinoma (OSCC), the cisplatin-resistance poses a major challenge for its …

Abstract In the Cauvery River (CR), indiscriminate discharge of waste causes unexplained
skeletal deformity in some fish species present in the water. To investigate this …

Piperine is a nitrogenous pungent substance exhibiting multifunctional pharmacological
properties. However, the mechanism underlying its anticancer potential is not well …

Abstract Nickel oxide nanoparticles (NiO-NPs) have extensively used in industrial and
consumer products. The present study conducted to gain more knowledge about the safe …