The nervous system development regulator neuropilin-1 as a potential prognostic marker and therapeutic target in brain cancer
Simple Summary Dysregulation of molecular mechanisms that regulate nervous system
development may be at the origin of brain tumors. We reviewed the role of neuropilin-1 …
development may be at the origin of brain tumors. We reviewed the role of neuropilin-1 …
Neuropilin-1 as a potential biomarker of prognosis and invasive-related parameters in liver and colorectal cancer: A systematic review and meta-analysis of human …
Simple Summary Neuropilin-1 (NRP1) is a transmembrane protein which has had recently
increased interest from cancer researchers. Liver cancer and colorectal cancer (CRC) are …
increased interest from cancer researchers. Liver cancer and colorectal cancer (CRC) are …
Plexin-A2 enables the proliferation and the development of tumors from glioblastoma derived cells
S Toledano, AD Sabag, N Ilan, T Liburkin-Dan… - Cell Death & …, 2023 - nature.com
The semaphorin guidance factors receptor plexin-A2 transduces sema6A and sema6B
signals and may mediate, along with plexin-A4, the anti-angiogenic effects of sema6A …
signals and may mediate, along with plexin-A4, the anti-angiogenic effects of sema6A …
Role of semaphorin 3A in kidney development and diseases
Y Sang, K Tsuji, H Nakanoh, K Fukushima, S Kitamura… - Diagnostics, 2023 - mdpi.com
Kidney diseases are worldwide public health problems affecting millions of people.
However, there are still limited therapeutic options against kidney diseases. Semaphorin 3A …
However, there are still limited therapeutic options against kidney diseases. Semaphorin 3A …
Glomerular endothelial cells are the coordinator in the development of diabetic nephropathy
T Li, K Shen, J Li, SWS Leung, T Zhu, Y Shi - Frontiers in Medicine, 2021 - frontiersin.org
The prevalence of diabetes is consistently rising worldwide. Diabetic nephropathy is a
leading cause of chronic renal failure. The present study aimed to explore the crosstalk …
leading cause of chronic renal failure. The present study aimed to explore the crosstalk …
Single-cell RNA-seq reveals the communications between extracellular matrix-related components and Schwann cells contributing to the earlobe keloid formation
T Gong, Y Wang, S Dong, X Ma, D Du, C Zou… - Frontiers in …, 2022 - frontiersin.org
Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive
accumulation of extracellular matrix (ECM) components, and another feature of pain/itching …
accumulation of extracellular matrix (ECM) components, and another feature of pain/itching …
Promotion of gastric tumor initiating cells in a 3D collagen gel culture model via YBX1/SPP1/NF-κB signaling
S Deng, L Li, S Xu, X Wang, T Han - Cancer Cell International, 2021 - Springer
Background The high potential for tumor recurrence and chemoresistance is a major
challenge of clinical gastric cancer treatment. Increasing evidence suggests that the …
challenge of clinical gastric cancer treatment. Increasing evidence suggests that the …
mRNA markers for survival prediction in glioblastoma multiforme patients: a systematic review with bioinformatic analyses
P Azimi, T Yazdanian, A Ahmadiani - BMC cancer, 2024 - Springer
Background Glioblastoma multiforme (GBM) is a type of fast-growing brain glioma
associated with a very poor prognosis. This study aims to identify key genes whose …
associated with a very poor prognosis. This study aims to identify key genes whose …
NK/DC crosstalk-modulating antitumor activity via Sema3E/PlexinD1 axis for enhanced cancer immunotherapy
The complex relationship between natural killer (NK) cells and dendritic cells (DCs) within
the tumor microenvironment significantly impacts the success of cancer immunotherapy …
the tumor microenvironment significantly impacts the success of cancer immunotherapy …
Transcriptomic profiling revealed plexin A2 downregulation with migration and invasion alteration in dacarbazine-treated primary melanoma cells
A Tyumentseva, A Averchuk, N Palkina… - Frontiers in …, 2021 - frontiersin.org
Melanoma is highly heterogeneous type of malignant neoplasm that is responsible for the
majority of deaths among other types of skin cancer. In the present study, we screened a list …
majority of deaths among other types of skin cancer. In the present study, we screened a list …