Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility
F Ibtisham, A Honaramooz - Cells, 2020 - mdpi.com
Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …
onto the next generation. SSCs also have the potential to provide important knowledge …
Options for fertility preservation in prepubertal boys
C Wyns, M Curaba, B Vanabelle… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …
American Society of Clinical Oncology recommendations on fertility preservation in cancer patients
Purpose To develop guidance to practicing oncologists about available fertility preservation
methods and related issues in people treated for cancer. Methods An expert panel and a …
methods and related issues in people treated for cancer. Methods An expert panel and a …
Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment
V Keros, K Hultenby, B Borgström… - Human …, 2007 - academic.oup.com
BACKGROUND Banking of testicular tissue from pre-pubertal boys before gonadotoxic
treatment is a crucial step in fertility preservation. We wanted to find optimal methods for …
treatment is a crucial step in fertility preservation. We wanted to find optimal methods for …
Formation of organotypic testicular organoids in microwell culture
S Sakib, A Uchida, P Valenzuela-Leon… - Biology of …, 2019 - academic.oup.com
Abstract Three-dimensional (3D) organoids can serve as an in vitro platform to study cell–
cell interactions, tissue development, and toxicology. Development of organoids with tissue …
cell interactions, tissue development, and toxicology. Development of organoids with tissue …
[HTML][HTML] Experimental methods to preserve male fertility and treat male factor infertility
Infertility is a prevalent condition that has insidious impacts on the infertile individuals, their
families, and society, which extend far beyond the inability to have a biological child …
families, and society, which extend far beyond the inability to have a biological child …
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation
BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
Long-term spermatogonial survival in cryopreserved and xenografted immature human testicular tissue
C Wyns, A Van Langendonckt, FX Wese… - Human …, 2008 - academic.oup.com
BACKGROUND Preservation of the male germ line in prepubertal boys undergoing
gonadotoxic treatment is a crucial consideration in terms of their future quality of life. As …
gonadotoxic treatment is a crucial consideration in terms of their future quality of life. As …
Male fertility preservation and restoration strategies for patients undergoing gonadotoxic therapies
KTD Tran, H Valli-Pulaski, A Colvin… - Biology of …, 2022 - academic.oup.com
Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …
is an insidious disease that impacts not only the ability to have a biological child but also the …
[HTML][HTML] Biomaterial strategies for the application of reproductive tissue engineering
Human reproductive organs are of vital importance to the life of an individual and the
reproduction of human populations. So far, traditional methods have a limited effect in …
reproduction of human populations. So far, traditional methods have a limited effect in …