Genome editing has been a transformative force in the life sciences and human medicine,
offering unprecedented opportunities to dissect complex biological processes and treat the …

Many peptide hormones form an α-helix on binding their receptors,,–, and sensitive methods
for their detection could contribute to better clinical management of disease. De novo protein …

Globally, more than 58 million people are chronically infected with Hepatitis C virus (HCV)
with 1.5 million new infections occurring each year. An effective vaccine for HCV is therefore …

Protein crystallization plays a central role in structural biology. Despite this, the process of
crystallization remains poorly understood and highly empirical, with crystal contacts, lattice …

The development of high‐performance photocatalytic systems for CO2 reduction is
appealing to address energy and environmental issues, while it is challenging to avoid …

Computationally designed multi-subunit assemblies have shown considerable promise for a
variety of applications, including a new generation of potent vaccines. One of the major …

The manufacture of high-performance photocatalytic systems based on earth-abundant
elements remains a key challenge, urging operative strategies for catalyst design. Herein …

Electrocatalytic and photocatalytic CO2 reduction by a heterobimetallic Cu/Fe–Mabiq
complex were examined and compared to the monometallic [Fe (Mabiq)]+. The …

Discrete protein assemblies ranging from hundreds of kilodaltons to hundreds of
megadaltons in size are a ubiquitous feature of biological systems and perform highly …

Many naturally occurring protein assemblies have dynamic structures that allow them to
perform specialized functions. For example, clathrin coats adopt a wide variety of …