The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD) is well established
for up to 1 or 2 years, but long-term outcome data are still limited. In this Review, we critically …

Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

Background Subthalamic stimulation reduces motor disability and improves quality of life in
patients with advanced Parkinson's disease who have severe levodopa-induced motor …

Freezing of gait is a common and disabling symptom in patients with parkinsonism,
characterised by sudden and brief episodes of inability to produce effective forward …

Continuous high-frequency deep brain stimulation (DBS) is a widely used therapy for
advanced Parkinson's disease (PD) management. However, the mechanisms underlying …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The
condition causes a heavy burden both on those affected, as well as their families. Accurate …

Objectives: Our objective was to compare long-term outcomes of deep brain stimulation
(DBS) of the globus pallidus interna (GPi) and subthalamic nucleus (STN) for patients with …

Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of
Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide …