Insights into the assembly and regulation of the bacterial divisome
TA Cameron, W Margolin - Nature Reviews Microbiology, 2024 - nature.com
The ability to split one cell into two is fundamental to all life, and many bacteria can
accomplish this feat several times per hour with high accuracy. Most bacteria call on an …
accomplish this feat several times per hour with high accuracy. Most bacteria call on an …
Macromolecular crowding, phase separation, and homeostasis in the orchestration of bacterial cellular functions
Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …
complexes in all cells, including bacteria. Crowding, together with physicochemical …
Kinetic control of shape deformations and membrane phase separation inside giant vesicles
A variety of cellular processes use liquid–liquid phase separation (LLPS) to create functional
levels of organization, but the kinetic pathways by which it proceeds remain incompletely …
levels of organization, but the kinetic pathways by which it proceeds remain incompletely …
[HTML][HTML] Wetting and complex remodeling of membranes by biomolecular condensates
Cells compartmentalize parts of their interiors into liquid-like condensates, which can be
reconstituted in vitro. Although these condensates interact with membrane-bound …
reconstituted in vitro. Although these condensates interact with membrane-bound …
[HTML][HTML] Biomolecular condensates modulate membrane lipid packing and hydration
Membrane wetting by biomolecular condensates recently emerged as a key phenomenon in
cell biology, playing an important role in a diverse range of processes across different …
cell biology, playing an important role in a diverse range of processes across different …
Biomolecular condensates in contact with membranes
A Mangiarotti, R Dimova - Annual Review of Biophysics, 2024 - annualreviews.org
Biomolecular condensates are highly versatile membraneless organelles involved in a
plethora of cellular processes. Recent years have witnessed growing evidence of the …
plethora of cellular processes. Recent years have witnessed growing evidence of the …
[HTML][HTML] Bacterial lipid biophysics and membrane organization
LMY Mitchison-Field, BJ Belin - Current Opinion in Microbiology, 2023 - Elsevier
The formation of lateral microdomains is emerging as a central organizing principle in
bacterial membranes. These microdomains are targets of antibiotic development and have …
bacterial membranes. These microdomains are targets of antibiotic development and have …
[HTML][HTML] Transient, nano-scale, liquid-like molecular assemblies coming of age
A Kusumi, TA Tsunoyama, KGN Suzuki… - Current Opinion in Cell …, 2024 - Elsevier
This review examines the dynamic mechanisms underlying cellular signaling,
communication, and adhesion via transient, nano-scale, liquid-like molecular assemblies on …
communication, and adhesion via transient, nano-scale, liquid-like molecular assemblies on …
How membranes influence intracellular phase separation
R Dimova - Nature Chemistry, 2024 - nature.com
Liquid–liquid phase separation (LLPS) within cells is a captivating phenomenon known to
aid the organization of cellular components; however, its complex kinetics have remained a …
aid the organization of cellular components; however, its complex kinetics have remained a …
[HTML][HTML] Biomolecular condensates as stress sensors and modulators of bacterial signaling
M Sasazawa, DT Tomares, WS Childers… - Plos …, 2024 - journals.plos.org
Microbes exhibit remarkable adaptability to environmental fluctuations. Signaling
mechanisms, such as two-component systems and secondary messengers, have long been …
mechanisms, such as two-component systems and secondary messengers, have long been …