Antimalarial drug resistance in Africa: the calm before the storm?
MD Conrad, PJ Rosenthal - The Lancet Infectious Diseases, 2019 - thelancet.com
Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
the treatment and control of malaria. In this Review, we summarise evolving patterns of …
Malaria epidemiology and interventions in Ethiopia from 2001 to 2016
HS Taffese, E Hemming-Schroeder… - Infectious diseases of …, 2018 - mednexus.org
Background: Ethiopia is one of the African countries where Plasmodium falciparum and P.
vivax co-exist. Monitoring and evaluation of current malaria transmission status is an …
vivax co-exist. Monitoring and evaluation of current malaria transmission status is an …
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
AA Fola, SM Feleke, H Mohammed, BG Brhane… - Nature …, 2023 - nature.com
Diagnosis and treatment of Plasmodium falciparum infections are required for effective
malaria control and are pre-requisites for malaria elimination efforts; hence we need to …
malaria control and are pre-requisites for malaria elimination efforts; hence we need to …
[HTML][HTML] A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa
L Ndwiga, KM Kimenyi, K Wamae, V Osoti… - International Journal for …, 2021 - Elsevier
Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …
[HTML][HTML] Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …
Genomic analysis of Plasmodium vivax describes patterns of connectivity and putative drivers of adaptation in Ethiopia
AM Kebede, E Sutanto, H Trimarsanto… - Scientific Reports, 2023 - nature.com
Ethiopia has the greatest burden of Plasmodium vivax in Africa, but little is known about the
epidemiological landscape of parasites across the country. We analysed the genomic …
epidemiological landscape of parasites across the country. We analysed the genomic …
Use cases for genetic epidemiology in malaria elimination
R Dalmat, B Naughton, TS Kwan-Gett, J Slyker… - Malaria journal, 2019 - Springer
Background While traditional epidemiological approaches have supported significant
reductions in malaria incidence across many countries, higher resolution information about …
reductions in malaria incidence across many countries, higher resolution information about …
Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms
S Auburn, S Getachew, RD Pearson… - The Journal of …, 2019 - academic.oup.com
Abstract The Horn of Africa harbors the largest reservoir of Plasmodium vivax in the
continent. Most of sub-Saharan Africa has remained relatively vivax-free due to a high …
continent. Most of sub-Saharan Africa has remained relatively vivax-free due to a high …
Diversity and Multiplicity of P. falciparum infections among asymptomatic school children in Mbita, Western Kenya
Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important
surrogate indicators for assessing malaria transmission intensity in different regions of …
surrogate indicators for assessing malaria transmission intensity in different regions of …
High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State, Ethiopia
Background Plasmodium falciparum resistance to series of anti-malarial drugs is a major
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …