Biological activity of oxadiazole and thiadiazole derivatives
UA Atmaram, SM Roopan - Applied Microbiology and Biotechnology, 2022 - Springer
The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-
known heterocycles, being a common and essential feature of a variety of natural products …
known heterocycles, being a common and essential feature of a variety of natural products …
Exploring recent developments on 1, 2, 4‐triazole: Synthesis and biological applications
R Sathyanarayana, B Poojary - Journal of the Chinese …, 2020 - Wiley Online Library
Triazoles are nitrogen‐bearing heterocycles. In the last few decades, researchers have
focused on fused heterocycles, as they have better pharmacological effect compared to …
focused on fused heterocycles, as they have better pharmacological effect compared to …
Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest
MS Ahamad, S Siddiqui, A Jafri, S Ahmad, M Afzal… - PloS one, 2014 - journals.plos.org
A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide
range of pharmacological activities. The search for antiproliferative agents that reduce skin …
range of pharmacological activities. The search for antiproliferative agents that reduce skin …
Development of adamantane scaffold containing 1, 3, 4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting …
MMS Wassel, YA Ammar, GAME Ali, A Belal… - Bioorganic …, 2021 - Elsevier
Abstract A new series of 1, 3, 4-thiadiazolo-adamantane derivatives were synthesized
through molecular hybridization approach, then used as starting material to synthesize …
through molecular hybridization approach, then used as starting material to synthesize …
Anticancer and Antioxidant activity of Zingiber officinale Roscoe rhizome
Dietary components present in foods, spices and herbs are source of natural compounds
viz. phenols, flavonoids, tocopherols, ascorbic acid and carotenoids with potential benefits …
viz. phenols, flavonoids, tocopherols, ascorbic acid and carotenoids with potential benefits …
Effectual anticancer potentiality of loaded bee venom onto fungal chitosan nanoparticles
AI Alalawy, HA El Rabey, FM Almutairi… - … journal of polymer …, 2020 - Wiley Online Library
Chitosan and its nanoparticles (NPs) could be extracted from numerous fungal species and
used as effectual carriers for bioactive compounds. The fungal chitosan (FC) was …
used as effectual carriers for bioactive compounds. The fungal chitosan (FC) was …
Recent development of 1, 2, 4-triazole-containing compounds as anticancer agents
X Wen, Y Zhou, J Zeng, X Liu - Current Topics in Medicinal …, 2020 - ingentaconnect.com
1, 2, 4-Triazole derivatives possess promising in vitro and in vivo anticancer activity, and
many anticancer agents such as fluconazole, tebuconazole, triadimefon, and ribavirin bear a …
many anticancer agents such as fluconazole, tebuconazole, triadimefon, and ribavirin bear a …
Unveiling the chemistry of 1, 3, 4‐oxadiazoles and thiadiazols: A comprehensive review
Oxadiazoles and thiadiazoles are malleable heterocycles that have recently generated
major interest in the field of medicinal chemistry. Compounds based on these moieties have …
major interest in the field of medicinal chemistry. Compounds based on these moieties have …
[HTML][HTML] Synthesis and anticancer activity of novel 3, 6-disubstituted 1, 2, 4-triazolo-[3, 4-b]-1, 3, 4-thiadiazole derivatives
G Charitos, DT Trafalis, P Dalezis, C Potamitis… - Arabian Journal of …, 2019 - Elsevier
The development of new antitumor agents is one of the most pressing research areas in
medicinal chemistry and medicine. The importance of triazole and thiadiazole rings as …
medicinal chemistry and medicine. The importance of triazole and thiadiazole rings as …
New fluorinated diarylureas linked to pyrrolo [2, 3-d] pyrimidine scaffold as VEGFR-2 inhibitors: Molecular docking and biological evaluation
M Adel, KAM Abouzid - Bioorganic Chemistry, 2022 - Elsevier
Abstract A series of pyrrolo [2, 3-d] pyrimidine linked to diarylureas were previously
discovered by our group as sorafenib fused congeners, which were endowed with more …
discovered by our group as sorafenib fused congeners, which were endowed with more …