Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

Tissue homeostasis is regulated by apoptosis, the cell-suicide programme that is executed
by proteases called caspases. The Bcl2 family of intracellular proteins is the central …

Mitochondrial morphological and ultrastructural changes occur during apoptosis and
autophagy, but whether they are relevant in vivo for tissue response to damage is unclear …

Apoptosis by Death Factor: Cell Skip to Main Content Advertisement Cell This journal offers
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We have identified two cell types, each using almost exclusively one of two different CD95
(APO‐1/Fas) signaling pathways. In type I cells, caspase‐8 was activated within seconds …

▪ Abstract Apoptosis, a physiological process for killing cells, is critical for the normal
development and function of multicellular organisms. Abnormalities in cell death control can …

Abstract CD95 (APO-1/Fas) is a prototype death receptor characterized by the presence of
an 80 amino acid death domain in its cytoplasmic tail. This domain is essential for the …

Fas (also called CD95 or APO-1), a member of a subgroup of the tumour necrosis factor
receptor superfamily that contain an intracellular death domain, can initiate apoptosis …

Endoplasmic reticulum (ER) stress is a major contributor to liver disease and hepatic
fibrosis, but the role it plays varies depending on the cause and progression of the disease …

" BH3 domain only" members of the BCL-2 family including the pro-apoptotic molecule BID
represent candidates to connect with proximal signal transduction. Tumor necrosis factor α …