Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the
most lethal of all gynaecological malignancies. This remarkable fluid, which contains a …

Radiotherapy has led to important clinical advances; existing cancer radiotherapy resistance
is one remaining major challenge. Recently, biophysical cues in the tumor …

This report investigates the role of compressive stress on ovarian cancer in a 3D custom
built bioreactor. Cells within the ovarian tumor microenvironment experience a range of …

Mesenchymal stem cells (MSCs) and their derivatives can be promising tools in oncology
including ovarian cancer treatment. This study aimed to determine the effect of HATMSC2 …

Ovarian cancer is the 5th most common and the deadliest gynecological cancer, with a 5-
year survival rate of less than 50 percent. Most deaths due to ovarian cancer are caused by …

Background Cancer development is strictly correlated to composition and physical
properties of the extracellular matrix. Particularly, a higher matrix stiffness has been …

Background Metastasis was the major cause of the high mortality in ovarian cancer.
Although some mechanisms of metastasis in ovarian cancer were proposed, few have been …

Ovarian cancer is a gynecological neoplasm that can be found in women, which, due to
diagnostic difficulties, is often detected at advanced stages when treatment becomes a …

Compressive stress enables the investigation of a range of cellular processes in which
forces play an important role, such as cell growth, differentiation, migration, and invasion …