Augmenting peripheral nerve regeneration with adipose-derived stem cells

L Jiang, T Mee, X Zhou, X Jia - Stem cell reviews and reports, 2022 - Springer
Peripheral nerve injuries (PNIs) are common and debilitating, cause significant health care
costs for society, and rely predominately on autografts, which necessitate grafting a nerve …

Adipose tissue stem cells in peripheral nerve regeneration—In vitro and in vivo

SC Rhode, JP Beier, T Ruhl - Journal of neuroscience research, 2021 - Wiley Online Library
After peripheral nerve injury, Schwann cells (SCs) are crucially involved in several steps of
the subsequent regenerative processes, such as the Wallerian degeneration. They promote …

Human platelet lysate stimulates neurotrophic properties of human adipose-derived stem cells better than Schwann cell-like cells

S Brambilla, M Guiotto, E Torretta, I Armenia… - Stem Cell Research & …, 2023 - Springer
Background Trauma-associated peripheral nerve injury is a widespread clinical problem
causing sensory and motor disabilities. Schwann cells (SCs) contribute to nerve …

Translational bioengineering strategies for peripheral nerve regeneration: opportunities, challenges, and novel concepts

KA Sarhane, C Qiu, TGW Harris… - Neural Regeneration …, 2023 - journals.lww.com
Peripheral nerve injuries remain a challenging problem in need of better treatment
strategies. Despite best efforts at surgical reconstruction and postoperative rehabilitation …

Potential of fibrin glue and mesenchymal stem cells (MSCs) to regenerate nerve injuries: a systematic review

AC Ortiz, SOM Fideles, KT Pomini, MZ Bellini… - Cells, 2022 - mdpi.com
Cell-based therapy is a promising treatment to favor tissue healing through less invasive
strategies. Mesenchymal stem cells (MSCs) highlighted as potential candidates due to their …

[HTML][HTML] Defining the regenerative effects of native spider silk fibers on primary Schwann cells, sensory neurons, and nerve‐associated fibroblasts

F Millesi, T Weiss, A Mann, M Haertinger… - The FASEB …, 2021 - ncbi.nlm.nih.gov
The search for a suitable material to promote regeneration after long‐distance peripheral
nerve defects turned the spotlight on spider silk. Nerve conduits enriched with native spider …

Three-dimensional engineered peripheral nerve: toward a new era of patient-specific nerve repair solutions

OA Selim, S Lakhani, S Midha, A Mosahebi… - … Engineering Part B …, 2022 - liebertpub.com
Reconstruction of peripheral nerve injuries (PNIs) with substance loss remains challenging
because of limited treatment solutions and unsatisfactory patient outcomes. Currently, nerve …

Role of adipose tissue grafting and adipose-derived stem cells in peripheral nerve surgery

TM Saffari, S Saffari, KS Vyas, S Mardini… - Neural Regeneration …, 2022 - journals.lww.com
The application of autologous fat grafting in reconstructive surgery is commonly used to
improve functional form. This review aims to provide an overview of the scientific evidence …

Adipose tissue-derived stem cells in plastic and reconstructive surgery: a bibliometric study

W Liu, K Shi, X Zhu, H Zhao, H Zhang, A Jones… - Aesthetic plastic …, 2021 - Springer
Background Due to the evolving nature of the applications of adipose tissue-derived stem
cells (ADSCs) and the rapidly growing body of scientific literature, it is difficult to generate a …

Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair

SH Chen, HK Kao, JR Wun, PY Chou, ZY Chen… - APL …, 2022 - pubs.aip.org
Peripheral nerve injuries are commonly occurring traumas of the extremities; functional
recovery is hindered by slow nerve regeneration (< 1mm/day) following microsurgical repair …