Current state of immunotherapy for glioblastoma

M Lim, Y Xia, C Bettegowda, M Weller - Nature reviews Clinical …, 2018 - nature.com
Glioma is the most common primary cancer of the central nervous system, and around 50%
of patients present with the most aggressive form of the disease, glioblastoma. Conventional …

Pseudoprogression of brain tumors

SC Thust, MJ van den Bent… - Journal of Magnetic …, 2018 - Wiley Online Library
This review describes the definition, incidence, clinical implications, and magnetic
resonance imaging (MRI) findings of pseudoprogression of brain tumors, in particular, but …

Advances in neuro-oncology imaging

KJ Langen, N Galldiks, E Hattingen… - Nature Reviews …, 2017 - nature.com
Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key …

Magnetic particle imaging: current and future applications, magnetic nanoparticle synthesis methods and safety measures

C Billings, M Langley, G Warrington, F Mashali… - International Journal of …, 2021 - mdpi.com
Magnetic nanoparticles (MNPs) have a wide range of applications; an area of particular
interest is magnetic particle imaging (MPI). MPI is an imaging modality that utilizes …

An electrochemical biosensor designed by using Zr-based metal–organic frameworks for the detection of glioblastoma-derived exosomes with practical application

Z Sun, L Wang, S Wu, Y Pan, Y Dong, S Zhu… - Analytical …, 2020 - ACS Publications
Glioblastoma (GBM) is one of the most fatal tumors in the brain, and its early diagnosis
remains technically challenging due to the complex repertoires of oncogenic alterations and …

A review of magnetic particle imaging and perspectives on neuroimaging

LC Wu, Y Zhang, G Steinberg, H Qu… - American Journal …, 2019 - Am Soc Neuroradiology
Magnetic particle imaging is an emerging tomographic technique with the potential for
simultaneous high-resolution, high-sensitivity, and real-time imaging. Magnetic particle …

Imaging glioblastoma posttreatment: progression, pseudoprogression, pseudoresponse, radiation necrosis

SB Strauss, A Meng, EJ Ebani… - Neuroimaging …, 2021 - neuroimaging.theclinics.com
Eighty percent of all malignant primary brain tumors diagnosed in the United States are
gliomas. 1 The current treatment paradigm for high-grade gliomas (grades III and IV) …

SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017)

M Martínez-Garcia, J Álvarez-Linera, C Carrato… - Clinical and …, 2018 - Springer
Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all
high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) …

Analyzing magnetic resonance imaging data from glioma patients using deep learning

B Menze, F Isensee, R Wiest, B Wiestler… - … medical imaging and …, 2021 - Elsevier
The quantitative analysis of images acquired in the diagnosis and treatment of patients with
brain tumors has seen a significant rise in the clinical use of computational tools. The …

PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival

G Batsios, P Viswanath, E Subramani, C Najac… - Scientific reports, 2019 - nature.com
90% of low-grade gliomas and secondary glioblastomas are characterized by mutations in
isocitrate dehydrogenase 1 (IDHmut). IDHmut produces the oncometabolite 2 …