Brain ischemia and reperfusion engage multiple independently-fatal terminal pathways
involving loss of membrane integrity in partitioning ions, progressive proteolysis, and …

Protein synthesis inhibition occurs in neurons immediately on reperfusion after ischemia and
involves at least alterations in eukaryotic initiation factors 2 (eIF2) and 4 (eIF4) …

Protein phosphatase-1 (PP1) plays a key role in dephosphorylation in numerous biological
processes such as glycogen metabolism, cell cycle regulation, smooth muscle contraction …

The regulatory-targeting subunit (RGL, also called GM) of the muscle-specific glycogen-
associated protein phosphatase PP1G targets the enzyme to glycogen where it modulates …

Phosphorylation has been implicated in the regulation of microtubule (MT) stability and
function by controlling the interactions between MTs and MT-associated proteins. We found …

Protein phosphorylation on serine and threonine residues is a widely distributed post-
translational modification on proteins that acts to regulate their function. Phosphoprotein …

[Frontiers in Bioscience, 4, d646-658, October 1, 1999] 646 MOLECULAR MECHANISMS
UNDERLYING INHIBITION OF PROTEIN PHOSPHATASES B Page 1 [Frontiers in …

Protein Ser/Thr phosphatase 5 is a 58-kDa protein containing a catalytic domain structurally
related to the catalytic subunits of protein phosphatases 1, 2A, and 2B and an extended N …

Budding yeast, Saccharomyces cerevisiae, and its close relatives are unique among
eukaryotes in having a single gene, GLC7, encoding protein phosphatase-1 (PP1). This …

Inhibitor 1 (I-1) is a protein inhibitor of protein phosphatase 1 (PP1), a major eukaryotic
Ser/Thr phosphatase. Nonphosphorylated I-1 is inactive, whereas phosphorylated I-1 is a …