Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation

K Essawi, W Hakami, MBN Khan, R Martin… - … Therapy Methods & …, 2023 - cell.com
CRISPR-Cas9-based therapeutic genome editing approaches hold promise to cure a variety
of human diseases. Recent findings demonstrate pre-existing immunity for the commonly …

Development of CRISPR-Cas Editing Tools for Therapeutic Genome Editing

K Luk - 2022 - repository.escholarship.umassmed …
The discovery and development of clustered, regularly interspaced, short palindromic
repeats and CRISPR-associated proteins (CRISPR-Cas) systems have revolutionized …