[HTML][HTML] The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group
The simultaneous intake of food and drugs can have a strong impact on drug release,
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy …
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy …
[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs
X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles
N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …
Safety of probiotics: functional fruit beverages and nutraceuticals
Over the last decade, fruit juice consumption has increased. Their rise in popularity can be
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …
Bile acid synthesis: from nature to the chemical modification and synthesis and their applications as drugs and nutrients
TM Šarenac, M Mikov - Frontiers in Pharmacology, 2018 - frontiersin.org
Bile acids (BAs) are amphiphilic molecules with 24 carbon atoms and consist of a
hydrophobic and a rigid steroid nucleus, to which are attached a hydrophilic hydroxyl group …
hydrophobic and a rigid steroid nucleus, to which are attached a hydrophilic hydroxyl group …
Pharmacological applications of bile acids and their derivatives in the treatment of metabolic syndrome
Apart from well-known functions of bile acids in digestion and solubilization of lipophilic
nutrients and drugs in the small intestine, the emerging evidence from the past two decades …
nutrients and drugs in the small intestine, the emerging evidence from the past two decades …
[HTML][HTML] Exploring the potential impact of probiotic use on drug metabolism and efficacy
Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …
supplements, but are also recommended in treating or preventing various gastrointestinal …
Antidiabetic plants for the treatment of type 2 diabetes mellitus and associated Bacterial infections
MA Tienda-Vázquez, EM Melchor-Martínez… - Processes, 2023 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the metabolic disease with the highest morbidity rates
worldwide. The condition is characterized by hyperglycemia, insulin resistance …
worldwide. The condition is characterized by hyperglycemia, insulin resistance …
Semisynthetic bile acids: a new therapeutic option for metabolic syndrome
S Lazarević, M Đanić, S Goločorbin-Kon… - Pharmacological …, 2019 - Elsevier
Bile acids are endogenous emulsifiers synthesized from cholesterol having a peculiar
amphiphilic structure. Appreciation of their beneficial effects on human health, recognized …
amphiphilic structure. Appreciation of their beneficial effects on human health, recognized …
Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double‐Blind …
Background. Oxidative stress and inflammation are closely related pathophysiological
processes, both occurring in type 2 diabetes mellitus (T2DM). In addition to the standard …
processes, both occurring in type 2 diabetes mellitus (T2DM). In addition to the standard …