Hair follicle morphogenesis depends on Wnt, Shh, Notch, BMP and other signaling
pathways interplay between epithelial and mesenchymal cells. The Wnt pathway plays an …

Embryonic hair follicle induction and formation are regulated by mesenchymal–epithelial
interactions between specialized dermal cells and epidermal stem cells that switch to a hair …

BAFF, a member of the TNF family, is a fundamental survival factor for transitional and
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …

Hair follicle (HF) development is the result of neuroectodermal–mesodermal interactions,
and can be divided into morphologically distinguishable stages (induction, organogenesis …

All ectodermal organs, eg hair, teeth, and many exocrine glands, originate from two adjacent
tissue layers: the epithelium and the mesenchyme. Similar sequential and reciprocal …

Hypohidrotic and anhidrotic ectodermal dysplasia (HED/EDA) is a rare genodermatosis
characterized by abnormal development of sweat glands, teeth, and hair. Three disease …

Defining the unique molecular features of progenitors and their niche requires a genome-
wide, whole-tissue approach with cellular resolution. Here, we co-isolate embryonic hair …

The membrane-bound form of Fas ligand (FasL) signals apoptosis in target cells through
engagement of the death receptor Fas, whereas the proteolytically processed, soluble form …

Hair follicle (HF) formation in developing embryonic skin requires stepwise signalling
between the epithelial epidermis and mesenchymal dermis, and their specialized …

Wnt/β-catenin and NF-κB signaling mechanisms provide central controls in development
and disease, but how these pathways intersect is unclear. Using hair follicle induction as a …