Autophagy is a self-eating catabolic pathway that contributes to liver homeostasis through its
role in energy balance and in the quality control of the cytoplasm, by removing misfolded …

Autophagy is the liver cell energy recycling system regulating a variety of homeostatic
mechanisms. Damaged organelles, lipids and proteins are degraded in the lysosomes and …

Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline
antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the …

Transarterial chemoembolization (TACE) is commonly used for treating advanced
hepatocellular carcinoma (HCC). However, the instability of lipiodol-drug emulsion and the …

Metastasis and recurrence severely impact the treatment effect of hepatocellular carcinoma
(HCC). HCC complicated with cholestasis is more prone to recurrence and metastasis …

We have previously shown that dysregulation of miR-21 functioned as an oncomiR in breast
cancer. The aim of the present study was to elucidate the mechanisms by which miR-21 …

Exosomes contribute substantially to the communication between tumor cells and normal
cells. Benefiting from the stable structure, circular RNAs (circRNAs) are believed to serve an …

Transarterial chemoembolization (TACE) is the first-line treatment for unresectable
intermediate-stage hepatocellular carcinoma (HCC). It is of high clinical significance to …

Recently, chloroquine (CQ) has been widely used to improve the efficacy of different
chemotherapy drugs to treat tumors. However, the effects of single treatment of CQ on liver …

Hepatocellular carcinoma (HCC) is a malignant tumor with poor prognosis. Surgical
resection is recommended for very early-stage and early-stage HCC, but HCC is still prone …