A multifaceted coating for hard tissue implants, with favorable osteogenesis, angiogenesis,
and osteoimmunomodulation abilities, would be of great value since it could improve …

The lack of a functional vascular supply has been identified as a major challenge limiting the
clinical introduction of stem cell-based bone tissue engineering (BTE) for the repair of large …

Bone marrow mesenchymal stem cells (BMSCs) are integral to bone remodeling and
homeostasis, as they are capable of differentiating into osteogenic and adipogenic lineages …

Aim: We investigated the role of induced endothelial cells (iECs) in mesenchymal stem cells
(MSCs)/iECs co-culture and assessed their osteogenic ability on silk fibroin nanofiber …

Co-culture of bone marrow stromal cells (BMSCs) and vascular endothelial cells (VECs) is a
promising strategy for better osteogenesis and pre-vascularization in bone tissue …

Chondrogenesis and mechanical stimulation of the cartilage template are essential for bone
formation through the endochondral ossification process in vivo. Recent studies have …

In vivo laser Doppler flowmetry (LDF) has previously been used to quantify blood perfusion
accurately at a single timepoint in the murine tibial metaphysis. However, this procedure …

Advanced technologies and their applications have undergone drastic changes over several
industrial revolutions. The third industrial revolution was associated with implying electronics …

Introduction: Biomechanical stimulation of cultured human osteoblast-like cells, which is
based on controlled mechanical vibration, has been previously indicated, but the exact …

Contemporary maxillofacial reconstructive approaches focus mainly on regenerating newly
formed functional tissue structures, rather than implantation of space-holding compartments …